that enhanced peroxynitrite formation occurs in atherosclerosis and could contribute to lipid
peroxidation in atherosclerosis. 24, 51 Taken together, these data indicate that catabolism of …

Although in therapeutic use for more than a century, the mode of cellular action of organic
nitrates remains incompletely understood. Despite ample experimental evidence from …

Endothelium-derived nitric oxide (eNO) is a multifunctional signaling molecule critically
involved in the maintenance of metabolic and cardiovascular homeostasis. In addition to its …

Background There is increasing evidence that loss of endothelium-derived NO is a major
factor in cardiovascular complication events, and that NO might exert antiatherosclerotic …

Following arterial occlusion, blood vessels respond by sprouting new capillaries (ie
angiogenesis) and by growing and remodelling pre-existing arterioles into physiologically …

Endothelium-derived nitric oxide (NO) is a paracrine factor that controls vascular tone,
inhibits platelet function, prevents adhesion of leukocytes, and reduces proliferation of the …

Nitric oxide (NO) was originally described as the principal endothelium-derived relaxing
factor, but it is now known to subserve a variety of functions throughout the body, both …

Nitric oxide (NO) is an intra-and inter-signaling molecule that regulates vessel dilatation,
neuronal transmission, cardiac contraction, immunomodulation, and stem cell differentiation …

Fifteen years after its discovery, NO has fully reached an established position in physiology,
medicine and therapeutics. It is difficult to find a biological function or a pathological …

Publisher Summary The nitric oxide (NO) donors are a diverse group of agents with unique
chemical structures and biochemical requirements for generation of NO. The diverse and …