Maspin belongs to the serpin superfamily and has been identified as a tumor suppressor
because it inhibits cell motility, invasion, and angiogenesis. However, its physiological …

This study aimed at investigating new mechanisms of carcinogenesis in thyroid cancer at the
molecular level and at finding potential protein markers involved in the initiation of the …

Results Maspin was only detected in papillary thyroid carcinoma (PTC) and it was negative
in all other studied thyroid tissues. In PTC 18/25 (72%) cases were maspin positive. Most of …

The serine protease inhibitor maspin has been reported to inhibit invasiveness and motility
of tumor cells. Additionally, a p53-dependent regulatory pathway of maspin in human cancer …

Maspin (mammary serpin) is a serine protease inhibitor member of the serpin family and a
class II tumor suppressor, whose expression is lost in many advanced cancers. Maspin has …

Maspin is a noninhibitory member of the serpin family that is down-regulated in breast
carcinoma but overexpressed in pancreatic carcinoma. There are no published data …

We evaluated the biological relevance of maspin expression in pancreatic ductal
adenocarcinoma and studied regulatory mechanisms of maspin gene activation in …

Maspin, a protein belonging to the serpin superfamily, seems to exert tumour-suppressive
activity. Its significance in ovarian cancer prognosis is currently under investigation. In the …

Maspin is a unique member of the serpin family, which inhibits tumor invasion and
metastasis of the human breast and prostate cancers. Immunohistochemical evaluation of …

Background: Maspin inhibits cell motility, invasion and metastasis. Loss or reduction in
maspin expression has been associated with tumoral progression. Methods: The presence …