The embryonic brain and spinal cord initially form through the process of neural tube closure
(NTC). NTC is thought to be highly similar between rodents and humans, and studies of …

Neurulation, the process of neural tube formation, is a complex morphogenetic event. In the
mammalian embryo, an understanding of the dynamic nature of neurulation has been …

In developing vertebrates, the neural tube forms from a sheet of neural ectoderm by complex
cell movements and morphogenesis. Convergent extension movements and the apical …

The development of the embryonic brain critically depends on successfully completing
cranial neural tube closure (NTC). Failure to properly close the neural tube results in …

During embryonic development, the central nervous system forms as the neural plate and
then rolls into a tube in a complex morphogenetic process known as neurulation. Neural …

Neural tube closure (NTC) is a fundamental process during vertebrate development and is
indispensable for the formation of the central nervous system. Here, using Xenopus laevis …

The closure of the neural tube (NT) in the human embryo has generally been described as a
continuous process that begins at the level of the future cervical region and proceeds both …

The developmental process of neurulation involves a series of coordinated morphological
events, which result in conversion of the flat neural plate into the neural tube, the primordium …

BACKGROUND Neural tube closure is a critical embryological process that requires the
coordination of many molecular and cellular events. Only recently has the molecular basis of …

The neural tube (NT), the embryonic precursor of the vertebrate brain and spinal cord, is
generated by a complex and highly dynamic morphological process. In mammals, the …