The oncocytic variant of poorly differentiated thyroid carcinoma shows a specific immune-related gene expression profile

J Metovic, C Vignale, L Annaratone… - The Journal of …, 2020 - academic.oup.com
Background Poorly differentiated thyroid cancer (PDTC) is a rare, follicular cell-derived
neoplasm with an unfavorable prognosis. The oncocytic variant of PDTC may be associated …

Immune profiling of thyroid carcinomas suggests the existence of two major phenotypes: an ATC-like and a PDTC-like

R Giannini, S Moretti, C Ugolini… - The Journal of …, 2019 - academic.oup.com
Objectives The understanding of the mechanisms underlying thyroid cancer immune escape
can lead to the identification of new molecular targets and/or efficacy biomarkers. For this …

Immune landscape of papillary thyroid cancer and immunotherapeutic implications

KJ Na, H Choi - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Although papillary thyroid cancer (PTC) is curable with excellent survival rate, patients with
dedifferentiated PTC suffer the recurrence or death. As cancer immune escape plays a …

Immune gene signature delineates a subclass of papillary thyroid cancer with unfavorable clinical outcomes

K Kim, S Jeon, TM Kim, CK Jung - Cancers, 2018 - mdpi.com
Papillary thyroid carcinoma (PTC) represents a heterogeneous disease with diverse clinical
outcomes highlighting a need to identify robust biomarkers with clinical relevance. We …

[HTML][HTML] Immune gene signature delineates a subclass of thyroid cancer with unfavorable clinical outcomes

J Zhi, J Yi, M Tian, H Wang, N Kang, X Zheng… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Thyroid cancer (THCA) is a heterogeneous disease with multiple clinical outcomes Immune
cells regulate its progression. Three immunomolecular subtypes (C1, C2, C3) were …

Identification of an immune-related signature indicating the dedifferentiation of thyroid cells

X Wang, W Peng, C Li, R Qin, Z Zhong, C Sun - Cancer Cell International, 2021 - Springer
Background Immune cells account for a large proportion of the tumour microenvironment in
anaplastic thyroid carcinomas (ATCs). However, the expression pattern of immune-related …

Papillary Thyroid Carcinoma Variants are Characterized by Co-dysregulation of Immune and Cancer Associated Genes

J Chakladar, WT Li, M Bouvet, EY Chang… - Cancers, 2019 - mdpi.com
Papillary thyroid carcinoma (PTC) variants exhibit different prognosis, but critical
characteristics of PTC variants that contribute to differences in pathogenesis are not well …

Significance of oncocytic features in poorly differentiated thyroid carcinoma—a bi-institutional experience

B Xu, DJ Lubin, S Dogan, RA Ghossein… - Virchows Archiv, 2023 - Springer
Poorly differentiated thyroid carcinoma (PDTC), defined by Turin criteria, comprises a subset
of high-grade follicular-derived thyroid carcinomas with intermediate prognosis. While …

Development and validation of a three-immune-related gene signature prognostic risk model in papillary thyroid carcinoma

X Gan, M Guo, Z Chen, Y Li, F Shen, J Feng… - Journal of …, 2021 - Springer
Purpose Increasing evidence indicates that there is a correlation between papillary thyroid
carcinoma (PTC) prognosis and the immune signature. Our goal was to construct a new …

Construction of a novel cuproptosis-related gene signature for predicting prognosis and estimating tumor immune microenvironment status in papillary thyroid …

L Wang, B Yao, J Yang, Z Tian, J He - BMC cancer, 2022 - Springer
Background Cuproptosis, a new form of programmed cell death, has been recently reported
to be closely related to tumor progression. However, the significance of cuproptosis-related …