Carcinogenesis may result from the action of any one or a combination of chemical,
physical, biologic, and/or genetic insults to cells. The process of carcinogenesis may be …

Cancer develops secondary to multiple genetic events. Each time a cell divides there is a
rare chance that a genetic error related to the carcinogenic process will occur. Thus …

Internationally renowned basic and clinical scientists provide an account of our best current
understanding of the genetics of cancer. These authoritative contributors describe in detail …

Intensive research efforts during the last several decades have increased our understanding
of carcinogenesis, and have identified a genetic basis for the multi-step process of cancer …

In the past 15 years, many of the mechanisms underlying the molecularorigins of cancer
have been uncovered, and a clear picture of the role ofoncogenes and tumor suppressor …

Cancer is a medical condition which has a molecular basis. Proto-oncogenes are the first
regulatory factors of this biological process. They act in transmitting signals, resulting as …

After a quarter century of rapid advances, cancer research has generated a rich and
complex body of knowledge, revealing cancer to be a disease involving dynamic changes in …

In this paper I will consider an aspect of carcinogenesis that needs further in-depth study
because it could be a major cause of human cancers. I am referring to the Damoclean …

Atumor isolated from a patient is a large aggregation of cancer cells, all of them descended
from a sin gle" founder" cell. The single ancestor was once a normal cell, with a normal …

THE past decade has witnessed great changes in our understanding of the molecular
origins of cancer. Much of this progress stems from the discovery of specific genes, the …