Systemic lupus erythematosus (SLE) is an autoimmune disease that attacks almost every
organ. The condition mostly happens to adults but is also found in children, and the latter …

Functional polarization of macrophages into M1 or M2 cells is an operationally useful,
simplified conceptual framework describing the plasticity of mononuclear phagocytes …

Plasticity and functional polarization are hallmarks of the mononuclear phagocyte system.
Here we review emerging key properties of different forms of macrophage activation and …

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Highlights•Evidence for macrophage reprogramming in vivo.•Macrophage polarization in
acute and chronic inflammation.•Resident macrophage subpopulations are functionally …

Macrophages perform critical functions for homeostasis and immune defense in tissues
throughout the body. These innate immune cells are capable of recognizing and clearing …

Macrophages are innate immune cells in the organism and can be found in almost tissues
and organs. They are highly plastic and heterogeneous cells and can participate in the …

Macrophages are a heterogeneous population of innate myeloid cells involved in health and
disease, which are the most functionally diverse cells of the hematopoietic system. The main …

Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue
macrophages are seeded in the early embryo before definitive hematopoiesis is …

Macrophages represent a heterogeneous cell population and are known to display a
remarkable plasticity. In response to distinct micro-environmental stimuli, eg, tumor stroma …