Bile acids (BAs) have many physiological roles and exhibit both toxic and protective
influences within the liver. Alterations in the BA profile may be the result of disease induced …

Objective Metabolomic studies suggest plasma levels of bile acids (BAs) are elevated
amongst subjects with non-alcoholic fatty liver disease (NAFLD) compared to healthy …

Non-alcoholic steatohepatitis (NASH) is a progressive inflammatory and fibrotic disease.
However, the progression mechanism of NASH is not well understood. Bile acids are …

Abstract Background and Aims The prevalence of nonalcoholic fatty liver disease (NAFLD)
and steatohepatitis (NASH) is increasing at an alarming rate. The role of bile acids in the …

Abstract Context Bile acids (BAs) are signaling molecules controlling energy homeostasis
that can be both toxic and protective for the liver. BA alterations have been reported in …

Background & Aims Non-alcoholic fatty liver disease (NAFLD) is characterized by dysbiosis.
The bidirectional effects between intestinal microbiota (IM) and bile acids (BA) suggest that …

Abstract Context Bile acids (BAs) are pivotal signaling molecules that regulate energy
metabolism and inflammation. Recent epidemiological studies have reported specific …

Background & Aims Through FXR and TGR5 signaling, bile acids (BAs) modulate lipid and
glucose metabolism, inflammation and fibrosis. Hence, BAs returning to the liver after enteric …

The histologic spectrum of nonalcoholic fatty liver disease (NAFLD) includes fatty liver
(NAFL) and steatohepatitis (NASH), which can progress to cirrhosis in up to 20% of NASH …

Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive fat deposition in the
liver in the absence of significant alcohol consumption. Dysregulated bile acid (BA) …