METHODS AND RESULTS Forty-eight participants came to the laboratory for four sessions
that presented a 2 (ethanol 0.5 g/kg versus placebo) 2 (nicotine-containing versus …

Epidemiological, clinical, and laboratory evidence has shown a positive correlation between
cigarette smoking and ethanol use, and previous studies suggest some commonality in the …

An extensive literature documents a close association between cigarette and alcohol use.
The joint pharmacological effects of alcohol and nicotine on smoking and drinking …

Evidence from alcohol self-administration studies suggests that nicotine replacement
therapy may influence subjective and behavioral responses to alcohol. However, its effect …

Background: Alcohol and nicotine, in the form of tobacco, are commonly co‐abused.
Nicotinic receptors also have been implicated in alcohol action. We designed the present …

Background: Recent studies have implicated central nicotinic cholinergic receptor systems
in the reinforcing properties of alcohol. In laboratory animals, mecamylamine, a central …

Non-daily smokers commonly smoke cigarettes following the consumption of alcohol, yet the
reason (s) for this remains poorly understood. The present study examined the impact of …

Observations in humans suggest that the initial use of tobacco occurs in close temporal
proximity to experimentation with alcohol. There have been relatively few research reports …

Separate and combined effects of nicotine and the nicotinic antagonist mecamylamine were
studied in 32 healthy volunteer smokers after overnight abstinence from smoking. Subjects …

The present study examined several pharmacological and behavioral treatments designed
to promote extinction of the responses to rewarding cigarette smoke cues. Pharmacological …