An orphan G protein-coupled receptor, termed 6H1, with∼ 30% sequence identity to P2Y
receptors has been proposed to be a P2Y receptor (p2y5) based solely on a radioligand …

A recently cloned G protein-coupled receptor (named the p2y7 receptor) with relatively low
sequence identity to previously cloned P2Y receptors was proposed to be a member of this …

Nucleotides signal through purinergic receptors such as the P2 receptors, which are
subdivided into the ionotropic P2X receptors and the metabotropic P2Y receptors. The …

The P2Y13 receptor has recently been identified as a new P2Y receptor sharing a high
sequence homology with the P2Y12 receptor as well as similar functional properties …

A P2Y receptor with 65% identity to mammalian P2Y6receptors, termed the p2y3 receptor,
was recently cloned from a chick brain cDNA library and was proposed to represent a novel …

A family of G protein-coupled P2Y receptors that are activated by adenine and uridine
nucleotides has been identified recently. Degenerate primers based on conserved …

The action of extracellular nucleotides, specifically the ability of adenine nucleotides to
induce coronary vasodilation and bradycardia, was first described more than 70 years ago …

The human P2Y12 receptor (P2Y12-R) is a member of the G protein coupled P2Y receptor
family, which is intimately involved in platelet physiology. We describe here the purification …

The functional activity of deoxyadenosine 5′(α‐thio) triphosphate (dATPαS) was assessed
at the cloned human P2Y1 receptor stably expressed in 1321N1 human astrocytoma cells …

Analysis of the P2Y family of nucleotide‐activated G‐protein‐coupled receptors has been
compromised by the lack of selective high‐affinity, high‐specific‐radioactivity radioligands …