Background This study examined the effect of synthetic oxytocin delivered intranasally on
acute pain sensitivity using a placebo-controlled, double-blind, within-participant crossover …

Objectives: This study examined whether the administration of intranasal oxytocin was
associated with pain sensitivity, endogenous pain inhibitory capacity, and negative mood …

Introduction Oxytocin (OXT) is a peptide hormone produced in the hypothalamus that plays a
neuromodulatory role in emotion, stress, and anxiety. Due to its multidimensional role, OXT …

Chronic neck and shoulder pain (CNSP) is a common musculoskeletal disorder in adults,
which is linked to hypersensitivity to noxious stimuli. The hormone oxytocin has been …

Background Approximately 1.7 million Americans sustain a traumatic brain injury (TBI) each
year and chronic pain is a common complication. Objective We studied the effects of …

Objective Intranasal oxytocin has been shown to affect human social and emotional
processing, but its potential to affect pain remains elusive. This randomized, placebo …

Background: Preclinical data suggest that oxytocin reduces hypersensitivity by actions in the
spinal cord, but whether it produces antinociception to acute stimuli is unclear. In this article …

Objectives: A review of the literature was conducted to assess the association between
oxytocin (OT) and pain. Methods: PsychInfo, PubMed, and Medline (EBSCO) research …

The neuropeptide oxytocin (OT) has been shown to play a modulatory role in nociception.
However, analgesic effects of OT in chronic pain conditions remain elusive and the neural …

BACKGROUND: Human research investigating the impact of intranasal oxytocin on
psychological processes has accelerated over the last two decades. No review of side …