Pharmacogenomics and pediatric asthmatic medications

C Lim, R Priefer - Journal of Respiration, 2022 - mdpi.com
Asthma is a respiratory condition often stemming from childhood, characterized by difficulty
breathing and/or chest tightness. Current treatment options for both adults and children …

Pharmacogenetics of pediatric asthma: current perspectives

J Perez-Garcia, A Espuela-Ortiz… - Pharmacogenomics …, 2020 - Taylor & Francis
Asthma is a chronic respiratory disease that affects 339 million people worldwide and has a
considerable impact on the pediatric population. Asthma symptoms can be controlled by …

Pharmacogenetics of childhood uncontrolled asthma

M Khare, S Piparia, KG Tantisira - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction Asthma is a heterogeneous, multifactorial disease with multiple genetic and
environmental risk factors playing a role in pathogenesis and therapeutic response …

Genetic predictors of response to therapy in childhood asthma

SW Turner - Molecular Diagnosis & Therapy, 2009 - Springer
Asthma is a common chronic condition in children, where the response to treatment can be
heterogeneous within a population. Genetic variations may partly explain the inconsistent …

Role of biomarkers in understanding and treating children with asthma: towards personalized care

JE Lang, KV Blake - Pharmacogenomics and Personalized …, 2013 - Taylor & Francis
Asthma is one of the most common chronic diseases affecting children. Despite publicized
expert panels on asthma management and the availability of high-potency inhaled …

Pharmacogenomics: A step forward precision medicine in childhood asthma

G Ferrante, S Fasola, V Malizia, A Licari, G Cilluffo… - Genes, 2022 - mdpi.com
Personalized medicine, an approach to care in which individual characteristics are used for
targeting interventions and maximizing health outcomes, is rapidly becoming a reality for …

Asthma pharmacogenomics: 2015 update

JS Davis, ST Weiss, KG Tantisira - Current allergy and asthma reports, 2015 - Springer
There is evidence that genetic factors are implicated in the observed differences in
therapeutic responses to the common classes of asthma therapy such as β2-agonists …

The use of pharmacogenomics, epigenomics, and transcriptomics to improve childhood asthma management: where do we stand?

N Farzan, SJ Vijverberg, M Kabesch… - Pediatric …, 2018 - Wiley Online Library
Asthma is a complex multifactorial disease and it is the most common chronic disease in
children. There is a high variability in response to asthma treatment, even in patients with …

Asthma pharmacogenetics: responding to the call for a personalized approach

VE Ortega, ME Wechsler - Current Opinion in Allergy and Clinical …, 2013 - journals.lww.com
It will be important to replicate previous genotypic associations in large clinical trial cohorts
as future pharmacogenetic studies continue to focus on genome-wide approaches and the …

Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium

N Farzan, SJ Vijverberg, AK Andiappan… - …, 2017 - Future Medicine
Aim: International collaboration is needed to enable large-scale pharmacogenomics studies
in childhood asthma. Here, we describe the design of the Pharmacogenomics in Childhood …