The advent of new therapies, ranging from inhaled corticosteroids (ICS) to biologics, has led
to advances in the management of pediatric patients with asthma. These therapies offer …

Asthma is characterized by reversible bronchial hyper-responsiveness and airway
inflammation, and encompasses a wide variety of patients with different clinical phenotypes …

Last year's review on adult and pediatric asthma highlighted reports related to asthma
genetics, the importance of upper airway management, the costs of asthma, and the …

Evidence shows that various early life exposures (high house dust mite levels, early
antibiotic use) may predispose susceptible individuals to the development of asthma, but the …

Asthma is a common disease characterized by airway inflammation and bronchorestriction.
There are several common categories of medications for treating asthma; however, not all …

Asthma affects an estimated 20 million people (~ 7% of the population) in the United States
and results in more than 5,000 deaths each year from complications [1, 2]. The financial …

Introduction: Asthma is a common condition that affects large numbers of children and
adults, yet the burden of disease is not equally distributed amongst groups. In the United …

Although there has been much progress, many findings have not been replicated and
currently known genetic loci only account for a fraction of variability in drug response. More …

Background To date, genome-wide association studies (GWASs) of inhaled corticosteroid
(ICS) response in asthmatic patients have focused primarily on lung function and …

One main area of pharmacogenomics is the discovery of new drugs and drug targets with
molecular genetic or genomic methods; the other is the study of how genomic differences …