Introduction: Asthma is no longer thought of as a single disease, but rather a collection of
varying symptoms expressing different disease patterns. One of the ongoing challenges is …

Genetic factors play a key role in determining the widely heterogeneous response to
pharmacological treatment detectable among asthmatics. In particular, polymorphisms of the …

Background Long‐acting beta2‐agonists (LABA) are recommended in asthma therapy;
however, not all asthma patients respond well to LABA. We performed a systematic review …

There is wide variability in the response to inhaled corticosteroids (ICS) in asthma. While
some of this heterogeneity of response is due to adherence and environmental causes …

An individual's response to anti‐asthma medication is likely to arise from a complex
interaction between social, environmental and inherited factors. Studies indicate that genetic …

Major classes of medication in asthma management include bronchodilating β2-agonists,
anti-inflammatory inhaled corticosteroids, leukotriene modifiers and theophyllines. However …

Background Asthma is a significant worldwide health issue affecting kids and adults. Asthma
management is mainly straightforward, but considering the associated co-morbidities, it is …

Variability in response to short-acting β2-agonists (eg, albuterol) among patients with
asthma from diverse racial/ethnic groups may contribute to asthma disparities. We sought to …

© Annals of Translational Medicine. All rights reserved. Ann Transl Med 2022; 10 (23): 1257|
https://dx. doi. org/10.21037/atm-22-5375 evidence make 17q12-21 the most promising …

Current asthma treatments are effective for most but not all patients. Asthma is classified as a
complex genetic disease with its pathogenesis and expression (severity) determined by the …