BACKGROUND: Previous studies in subjects with a history of stroke have shown that white
matter hyperintensities (WMH) on MRI are associated with increased risk of death. However …

We examined the association of accelerated progression of white matter hyperintensities
(WMH) with mortality outcomes in 534 older subjects at risk for cardiovascular disease …

Many research studies have demonstrated asymptomatic white matter hyperintensities
(WMHs) in older adults, which are postulated to be ischemic in origin. We hypothesized that …

PURPOSE: To prospectively determine whether there is an association between brain white
matter signal hyperintensities on magnetic resonance (MR) images and potential risk factors …

The etiology of white matter hyperintensities (WMH) seen on T2-weighted cranial magnetic
resonance images is a matter of debate. We investigated deep and periventricular WMH in …

Background and Purpose We undertook this study to evaluate the frequency and risk factors
of white matter hyperintensities seen on T2-weighted MR imaging. We examined cohorts of …

Background: White matter hyperintensity (WMH) is prevalent in older adults aged 60 and
above. A large proportion of people with WMH have not experienced stroke and little has …

Background: The association of white matter hyperintensities (WMH) with age-related
vascular and neurodegenerative pathologies remains incompletely understood. Objective …

Background and Purpose—We have previously reported that several “silent” infarcts found
on magnetic resonance imaging (MRI) were a risk factor for stroke. Several recent reports …

Objective: To determine which vascular pathology measure most strongly correlates with
white matter hyperintensity (WMH) accumulation over time, and whether Alzheimer disease …