Antimicrobial peptides as an opportunity against bacterial diseases

S Galdiero, A Falanga, R Berisio… - Current Medicinal …, 2015 - ingentaconnect.com
Antimicrobial peptides (AMPs) are an heterogeneous group of small amino acidic molecules
produced by the innate immune system of a variety of organisms encompassing all orders of …

DRAMP 2.0, an updated data repository of antimicrobial peptides

X Kang, F Dong, C Shi, S Liu, J Sun, J Chen, H Li, H Xu… - Scientific data, 2019 - nature.com
Abstract Data Repository of Antimicrobial Peptides (DRAMP, http://dramp. cpu-bioinfor. org/)
is an open-access comprehensive database containing general, patent and clinical …

Antimicrobial peptides and cell-penetrating peptides: non-antibiotic membrane-targeting strategies against bacterial infections

X Huang, G Li - Infection and Drug Resistance, 2023 - Taylor & Francis
The prevalence of antimicrobial resistance (AMR) has been rising quickly in recent years.
AMR has emerged as a significant obstacle to the treatment of infectious diseases, and …

The role of antimicrobial peptides in human skin and in skin infectious diseases

B Schittek, M Paulmann, I Senyurek… - … disorders-drug targets …, 2008 - ingentaconnect.com
Antimicrobial peptides or proteins (AMPs) represent an ancient and efficient innate defense
mechanism which protects interfaces from infection with pathogenic microorganisms. In …

Antimicrobial peptides (AMPs): a patent review (2015–2020)

G Annunziato, G Costantino - Expert Opinion on Therapeutic …, 2020 - Taylor & Francis
Introduction: Antimicrobial peptides are a large class of compounds that are part of innate
immune response found among all classes of life and are considered promising compounds …

Recent advances in design of antimicrobial peptides and polypeptides toward clinical translation

Y Jiang, Y Chen, Z Song, Z Tan, J Cheng - Advanced Drug Delivery …, 2021 - Elsevier
The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

Antimicrobial peptides (AMPs): peptide structure and mode of action

YK Park, KS Hahm - BMB Reports, 2005 - koreascience.kr
Antimicrobial peptides (AMPs) have been isolated and characterized from tissues and
organisms representing virtually every kingdom and phylum. Their amino acid composition …

Antimicrobial peptides with protease stability: progress and perspective

C Shao, Y Zhu, Z Lai, P Tan, A Shan - Future Medicinal Chemistry, 2019 - Taylor & Francis
Antimicrobial peptides have attracted decades of attention as potential candidates for
addressing multidrug-resistant infections; however, their dismal record of immature stability …

Short AntiMicrobial Peptides (SAMPs) as a class of extraordinary promising therapeutic agents

S Ramesh, T Govender, HG Kruger… - Journal of Peptide …, 2016 - Wiley Online Library
The emergence of multidrug resistant bacteria has a direct impact on global public health
because of the reduced potency of existing antibiotics against pathogens. Hence, there is a …

The road from host-defense peptides to a new generation of antimicrobial drugs

A Boto, JM Pérez de la Lastra, CC González - Molecules, 2018 - mdpi.com
Host-defense peptides, also called antimicrobial peptides (AMPs), whose protective action
has been used by animals for millions of years, fulfill many requirements of the …