Resistance mechanisms to antimicrobial peptides in gram-positive bacteria

L Assoni, B Milani, MR Carvalho… - Frontiers in …, 2020 - frontiersin.org
With the alarming increase of infections caused by pathogenic multidrug-resistant bacteria
over the last decades, antimicrobial peptides (AMPs) have been investigated as a potential …

Antimicrobial peptides: interaction with model and biological membranes and synergism with chemical antibiotics

A Hollmann, M Martinez, P Maturana… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown
antimicrobial activity against a wide range of bacterial species, including multiresistant …

Antimicrobial peptides (AMPs): The quintessential 'offense and defense'molecules are more than antimicrobials

S Patel, N Akhtar - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Antimicrobial peptides (AMPs) are cationic amphiphilic molecules with α-helix or β-sheet
linear motifs and linear or cyclic configurations. For their role in 'defense and offense', they …

Antimicrobial peptides: classification, design, application and research progress in multiple fields

Y Huan, Q Kong, H Mou, H Yi - Frontiers in microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and
they are an important part of the innate immune system of different organisms. AMPs have a …

The critical and multifunctional roles of antimicrobial peptides in dermatology

T Takahashi, RL Gallo - Dermatologic clinics, 2017 - derm.theclinics.com
Skin is the physical and immunologic armor of the body. Both the physical and immune
defense system of the skin combine to accomplish functions essential to life, including …

Antimicrobial peptides and their analogs: searching for new potential therapeutics

K Midura-Nowaczek… - Perspectives in medicinal …, 2014 - journals.sagepub.com
Antimicrobial peptides (AMPs) are an essential part of innate immunity. These compounds
have been considered as potential therapeutics because of their broad-spectrum activities …

Short antimicrobial peptides as cosmetic ingredients to deter dermatological pathogens

M Rahnamaeian, A Vilcinskas - Applied microbiology and biotechnology, 2015 - Springer
Antimicrobial peptides (AMPs) are components of the innate immune system in many
species of animals. Their diverse spectrum of activity against microbial pathogens, both as …

Antimicrobial peptides: Molecular design, structure-function relationship, and biosynthesis optimization

Y Hao, J Wang, C de la Fuente-Nunez… - Frontiers in …, 2022 - frontiersin.org
The long-term use of antibiotics has accelerated the emergence of antibiotic-resistant
bacteria (ARB). Annual global death due to antibiotic resistance is over 700,000 in 2014, it is …

Advances in development of antimicrobial peptidomimetics as potential drugs

N Molchanova, PR Hansen, H Franzyk - Molecules, 2017 - mdpi.com
The rapid emergence of multidrug-resistant pathogens has evolved into a global health
problem as current treatment options are failing for infections caused by pan-resistant …

Antimicrobial peptides: a new frontier in antifungal therapy

G Buda De Cesare, SA Cristy, DA Garsin, MC Lorenz - MBio, 2020 - Am Soc Microbiol
Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …