Positive selection for single amino acid change promotes substrate discrimination of a plant volatile-producing enzyme

TJ Barkman, TR Martins, E Sutton… - Molecular Biology and …, 2007 - academic.oup.com
We used a combined evolutionary and experimental approach to better understand enzyme
functional divergence within the SABATH gene family of methyltransferases (MTs). These …

A collaborative classroom investigation of the evolution of SABATH methyltransferase substrate preference shifts over 120 My of flowering plant history

NM Dubs, BR Davis, V de Brito… - Molecular Biology …, 2022 - academic.oup.com
Next-generation sequencing has resulted in an explosion of available data, much of which
remains unstudied in terms of biochemical function; yet, experimental characterization of …

Evolution and Function of the Populus SABATH Family Reveal That a Single Amino Acid Change Results in a Substrate Switch

XM Han, Q Yang, YJ Liu, ZL Yang… - Plant and Cell …, 2018 - academic.oup.com
Evolutionary mechanisms of substrate specificities of enzyme families remain poorly
understood. Plant SABATH methyltransferases catalyze methylation of the carboxyl group of …

Plant SABATH Methyltransferases: Diverse Functions, Unusual Reaction Mechanisms and Complex Evolution

W Wang, H Guo, JL Bowman… - Critical Reviews in Plant …, 2024 - Taylor & Francis
It has been a quarter century since salicylic acid methyltransferase, the founding member of
the plant SABATH enzyme family, was discovered. From making methyl benzoate to …

Enzymatic, expression and structural divergences among carboxyl O-methyltransferases after gene duplication and speciation in Nicotiana

F Hippauf, E Michalsky, R Huang, R Preissner… - Plant molecular …, 2010 - Springer
Methyl salicylate and methyl benzoate have important roles in a variety of processes
including pollinator attraction and plant defence. These compounds are synthesized by …

S-adenosyl-L-methionine: salicylic acid carboxyl methyltransferase, an enzyme involved in floral scent production and plant defense, represents a new class of plant …

JR Ross, KH Nam, JC D'Auria, E Pichersky - Archives of biochemistry and …, 1999 - Elsevier
S-Adenosyl-l-methionine: salicylic acid carboxyl methyltransferase (SAMT) was partially
purified from petals of the annual California plant Clarkia breweri. SAMT catalyzes the …

Novel S-adenosyl-L-methionine: salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is not …

F Negre, N Kolosova, J Knoll, CM Kish… - Archives of Biochemistry …, 2002 - Elsevier
Using a functional genomic approach we have isolated and characterized a cDNA that
encodes a salicylic acid carboxyl methyltransferase (SAMT) from Antirrhinum majus. The …

Functional analysis of a tomato salicylic acid methyl transferase and its role in synthesis of the flavor volatile methyl salicylate

D Tieman, M Zeigler, E Schmelz, MG Taylor… - The Plant …, 2010 - Wiley Online Library
Methyl salicylate (MeSA) is a volatile plant secondary metabolite that is an important
contributor to taste and scent of many fruits and flowers. It is synthesized from salicylic acid …

A SABATH Methyltransferase from the moss Physcomitrella patens catalyzes S-methylation of thiols and has a role in detoxification

N Zhao, JL Ferrer, HS Moon, J Kapteyn, X Zhuang… - Phytochemistry, 2012 - Elsevier
Known SABATH methyltransferases, all of which were identified from seed plants, catalyze
methylation of either the carboxyl group of a variety of low molecular weight metabolites or …

Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family

C Zubieta, JR Ross, P Koscheski, Y Yang… - The Plant …, 2003 - academic.oup.com
Recently, a novel family of methyltransferases was identified in plants. Some members of
this newly discovered and recently characterized methyltransferase family catalyze the …