Background Hereditary transthyretin-mediated amyloidosis is a rare, progressive and
potentially life-limiting multisystem disease, affecting every aspect of a patient's life …

Background Amyloidosis represents a rare yet heterogeneous multi-system disorder
associated with a grave prognosis and an enormous psycho-emotional strain on patients …

Abstract Background Hereditary transthyretin (ATTRv) amyloidosis is a progressive
multisystemic disease of adult-onset that arises from an inherited mutation in the …

Background Hereditary transthyretin (hATTR) amyloidosis is a rare, systemic, progressive,
and life-threatening disease in which transthyretin proteins misfold and aggregate as …

Background Hereditary transthyretin-mediated amyloidosis, also known as ATTRv
amyloidosis (v for variant), is a rare, autosomal dominant, fatal disease, in which systemic …

Background Systemic amyloidosis is caused by the deposition of misfolded protein
aggregates in tissues, leading to progressive organ dysfunction and death. Epidemiological …

Transthyretin amyloidosis (ATTR amyloidosis) is a disease caused by deposition of
transthyretin fibrils in organs and tissues, which causes their dysfunction. The clinical …

Background Amyloidosis is a rare multi-system disorder associated with frequently delayed
diagnosis, enormous disease burden and psychosocial distress. Methods Systematic …

Introduction Transthyretin amyloidosis (ATTR amyloidosis), whether manifesting as familial
amyloid polyneuropathy (ATTR-PN) or cardiomyopathy (ATTR-CM), is a progressive …

Background Hereditary ATTR amyloidosis with polyneuropathy, also known as Familial
Amyloidotic Polyneuropathy (FAP), is a rare, inherited, progressively debilitating disease …