Evaluation of ocrelizumab in older progressive multiple sclerosis patients

S Epstein, KT Fong, PL De Jager, L Levine… - Multiple Sclerosis and …, 2021 - Elsevier
Background Seminal trials evaluating anti-CD20 therapy in progressive MS primarily found
benefit in younger, less-disabled patients with more inflammatory disease activity. The risks …

Real‐world evaluation of ocrelizumab in multiple sclerosis: A systematic review

X Montalban, PM Matthews, A Simpson… - Annals of clinical …, 2023 - Wiley Online Library
Across its clinical development program, ocrelizumab demonstrated efficacy in improving
clinical outcomes in multiple sclerosis, including annualized relapse rates and confirmed …

Real‐world experience of ocrelizumab in multiple sclerosis in a Spanish population

E Fernandez‐Diaz, JA Perez‐Vicente… - Annals of Clinical …, 2021 - Wiley Online Library
Objective Pivotal trial have shown that patients with multiple sclerosis (MS) receiving
ocrelizumab had better outcomes. However, data on ocrelizumab in clinical practice are …

Ocrelizumab B-cell repopulation-guided extended interval dosing versus standard dosing–similar clinical efficacy with decreased immunoglobulin M deficiency rates

T Rempe, A Elfasi, E Rodriguez, M Vasquez… - Multiple Sclerosis and …, 2023 - Elsevier
Background Ocrelizumab (OCR) is a humanized anti-CD20 monoclonal antibody used in
treatment of multiple sclerosis. The standard dosing (SD) regimen consists of OCR …

Safety profile of ocrelizumab for the treatment of multiple sclerosis: a systematic review

HS Ng, CL Rosenbult, H Tremlett - Expert Opinion on Drug Safety, 2020 - Taylor & Francis
Introduction We systematically reviewed adverse events (AEs) for ocrelizumab for multiple
sclerosis (MS). Areas covered We searched Medline, Embase, Web of Science, and …

Tolerability and safety of switching from rituximab to ocrelizumab: evaluating factors associated with infusion related reactions

E Alvarez, KV Nair, S Sillau, I Shelton… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background Ocrelizumab and rituximab are frequently used treatments for multiple sclerosis
(MS). Data on switching from rituximab to ocrelizumab is limited. Objectives To assess the …

Real-world experience of ocrelizumab in multiple sclerosis in an Arab population

B Garcia-Cañibano, S Ouanes… - Journal of Drug …, 2021 - Taylor & Francis
Objective Pivotal clinical trials revealed good clinical efficiency of ocrelizumab while having
a good safety profile in the management of multiple sclerosis (MS). However, real-world data …

Design of a non-interventional post-marketing study to assess the long-term safety and effectiveness of ocrelizumab in German real world multiple sclerosis cohorts …

P Dirks, V Zingler, J Leemhuis, H Berthold… - BMC neurology, 2020 - Springer
Background Multiple sclerosis (MS) is a chronic disease that requires lifelong treatment. A
highly effective drug not only for relapsing but also for progressive forms of MS with a …

[引用][C] Long-term safety and efficacy of ocrelizumab in patients with relapsing-remitting multiple sclerosis: week 144 results of a phase II, randomised, multicentre trial

L Kappos, D Li, P Calabresi, P O'Connor, A Bar-Or… - 28th congress of the …, 2012

Real world study of ocrelizumab in multiple sclerosis: Kuwait experience

R Alroughani, M AlMojel, J Al-Hashel… - Multiple Sclerosis and …, 2023 - Elsevier
Background Ocrelizumab is a humanized anti-CD20 antibody that has been approved for
the treatment of patients with multiple sclerosis (MS). Real-world data in the Middle East is …