Atrial fibrillation (AF) is the most frequent arrhythmia and is associated with increased
morbidity and mortality. Current drugs for AF treatment have moderate efficacy and increase …

Electrical remodeling refers to any change in electrical function that promotes atrial
fibrillation (AF). A key advance in understanding the mechanisms of AF has been the …

This review focuses on the (mal) adaptive processes in atrial excitation-contraction coupling
occurring in patients with chronic atrial fibrillation. Cellular remodeling includes shortening …

Atrial fibrillation (AF) is the most frequently encountered clinical arrhythmia and is associated
with increased morbidity and mortality. Ectopic activity and reentry are considered major …

Atrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity
and mortality. There have been significant management advances over the past 2 decades …

Atrial fibrillation (AF) causes substantial morbidity and mortality. It may be triggered and
sustained by either reentrant or nonreentrant electrical activity. Human atrial cellular …

Atrial fibrillation (AF) remains a major clinical problem (Nattel et al., 2021). Conceptually, AF
requires a trigger, often in the form of ectopic (triggered) activity, and a vulnerable substrate …

Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia and has a significant impact on
morbidity and mortality. Current antiarrhythmic drugs for AF suffer from limited safety and …

Although atrial fibrillation (AF) is the most commonly encountered cardiac arrhythmia, the
basic mechanisms underlying this disorder remain incompletely understood. During the past …

Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia in the clinical
setting. It is associated with substantial cardiovascular morbidity and mortality. Recent …