Formation of macrophage‐derived foam cells is a hallmark in earlier stages of
atherosclerosis (AS). Increased cholesterol efflux from macrophage foam cells promote …

Atherosclerosis can be regarded as a chronic disease derived from the interaction between
disordered lipoproteins and an unsuitable immune response. The evolution of foam cells is …

The accumulation of cholesterol in macrophages could induce the formation of foam cells
and increase the risk of developing atherosclerosis. We wonder if quercetin, one of …

Foam cells are the main pathological components of atherosclerosis. Therapies reducing
foam cell formation can effectively prevent atherosclerotic diseases and cardiovascular …

Aims The accumulation of lipids in macrophages contributes to the development of
atherosclerosis. Cholesterol efflux of lipid-loaded macrophages mediated by ATP binding …

Paeonol, a phenolic component purified from Paeonia suffruticosa (Cortex Moutan), is used
in traditional Chinese medicine to treat inflammatory diseases. However, little is known …

PPARα, β/δ, and γ regulate genes involved in the control of lipid metabolism and
inflammation and are expressed in all major cell types of atherosclerotic lesions. In vitro …

Foam cells are typical components of atherosclerotic plaques, where they actively
participate in the intracellular cholesterol accumulation. Onset and further progression of …

Lipid‐laden macrophages are considered as the main source of foam cells in
atherosclerosis; however, the mechanism for macrophage foam cell formation remains …

In vitro experiments have demonstrated that exogenous phospholipid transfer protein
(PLTP), ie purified PLTP added to macrophage cultures, influences ABCA1-mediated …