A randomized controlled pilot study of adherence to transfusion strategies in cardiac surgery

N Shehata, LA Burns, H Nathan, P Hebert… - …, 2012 - Wiley Online Library
BACKGROUND: It is important to determine the optimal hemoglobin (Hb) concentration for
red blood cell (RBC) transfusion for patients undergoing cardiac surgery because increased …

Transfusion Requirements in Cardiac Surgery III (TRICS III): study design of a randomized controlled trial

N Shehata, R Whitlock, DA Fergusson… - Journal of cardiothoracic …, 2018 - Elsevier
Objectives To determine if a restrictive transfusion threshold is noninferior to a higher
threshold as measured by a composite outcome of mortality and serious morbidity. Design …

Lowering the hemoglobin threshold for transfusion in coronary artery bypass procedures: effect on patient outcome

AW Bracey, R Radovancevic, SA Riggs… - …, 1999 - Wiley Online Library
BACKGROUND: There is controversy regarding the application of transfusion triggers in
cardiac surgery. The goal of this study was to determine if lowering the hemoglobin …

Safe application of a restrictive transfusion protocol in moderate-risk patients undergoing cardiac operations

HK Song, C Von Heymann, CM Jespersen… - The Annals of Thoracic …, 2014 - Elsevier
Background Perioperative red blood cell transfusion is associated with adverse outcomes
after cardiac operations. Although restrictive transfusion protocols have been developed …

On the need for improved transfusion indicators in cardiac surgery

LT Goodnough, GJ Despotis, CW Hogue Jr… - The Annals of thoracic …, 1995 - Elsevier
Guidelines for transfusion practice have had limited impact in altering physician transfusion
behavior in patients undergoing cardiac operations. This may be due to a lack of consensus …

Transfusion requirements after cardiac surgery: the TRACS randomized controlled trial

LA Hajjar, JL Vincent, FRBG Galas, RE Nakamura… - Jama, 2010 - jamanetwork.com
Context Perioperative red blood cell transfusion is commonly used to address anemia, an
independent risk factor for morbidity and mortality after cardiac operations; however …

Efforts to change transfusion practice and reduce transfusion rates are effective in coronary artery bypass surgery

JJ Andreasen, JE Sindby, BC Brocki… - Journal of cardiothoracic …, 2012 - Elsevier
OBJECTIVES: Efforts to decrease allogeneic blood transfusion and avoid unnecessary
transfusions in cardiac surgery are important because transfusions are associated with …

Patient blood management in cardiac surgery results in fewer transfusions and better outcome

I Gross, B Seifert, A Hofmann, DR Spahn - Transfusion, 2015 - Wiley Online Library
Background The aim of this study was to investigate the impact of the introduction of a
patient blood management (PBM) program in cardiac surgery on transfusion incidence and …

Anemia and patient blood management in cardiac surgery—literature review and current evidence

A Dhir, DK Tempe - Journal of cardiothoracic and vascular …, 2018 - jcvaonline.com
The prevalence of anemia is high in patients undergoing cardiac surgery. There is enough
evidence that the presence of anemia increases perioperative mortality and morbidity both …

Transfusion triggers for guiding RBC transfusion for cardiovascular surgery: a systematic review and meta-analysis

GF Curley, N Shehata, CD Mazer, GMT Hare… - Critical care …, 2014 - journals.lww.com
Objective: Restrictive red cell transfusion is recommended to minimize risk associated with
exposure to allogeneic blood. However, perioperative anemia is an independent risk factor …