The amyloid β protein has been identified as an important component of both
cerebrovascular amyloid and amyloid plaques of Alzheimer's disease and Down syndrome …

In an attempt to resolve the relative influences of major genes, multifactorial heritability, and
cohort effects on the susceptibility to Alzheimer disease (AD), complex segregation analysis …

In this article, the author focuses on genetic risk factor for Alzheimer's disease, and mentions
research work of geneticist Allen Roses on the same. The author also mentions genetic …

Mutations in the gene encoding the protein presenilin-1 are the most common cause of
familial Alzheimer's disease and they often produce a different disease course from sporadic …

Screening for the APP717 mutation in 5 further families with early onset Alzheimer's disease
failed to reveal further cases with this variant. Screening a further 100 normal individuals for …

Alzheimer's disease (AD), the most common cause of dementia in aged populations, is
believed to be caused by both environmental factors and genetic variations. Extensive …

The gene encoding the beta-amyloid precursor protein has been assigned to human
chromosome 21, as has a gene responsible for at least some cases of familial Alzheimer …

Linkage analysis was used to search the genome for chromosomal regions harboring
familial Alzheimer's disease genes. Markers on chromosome 14 gave highly significant …

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The paper by Tomita and colleagues (1) completes a series of experiments carried out in
many laboratories (2–4), which all lead to the same conclusion. Mutations in all three of the …