Antiphospholipase A2 receptor autoantibody guided diagnosis and treatment of membranous nephropathy: a new personalized medical approach

RJ Glassock - Clinical Journal of the American Society of …, 2014 - journals.lww.com
Medical care is entering into a new phase of" personalized" medical care in which diagnosis
and management are tailored to the specific aspects of individual patients. This approach is …

The relationship between anti-phospholipase A2 receptor antibody and idiopathic membranous nephropathy

W Lin, H Li, X Li, Y Qin, Y Su, Y Yu, Y Guan… - Zhonghua nei ke za …, 2015 - europepmc.org
Objective To explore the value of anti-phospholipase A2 receptor (PLA2R) antibody in the
diagnosis and disease activity monitoring of idiopathic membranous nephropathy (IMN) …

Anti-phospholipase A2 receptor antibody in membranous nephropathy

W Qin, LH Beck Jr, C Zeng, Z Chen, S Li… - Journal of the …, 2011 - journals.lww.com
The M-type phospholipase A2 receptor (PLA2R) is a target autoantigen in adult idiopathic
membranous nephropathy (MN), but the prevalence of autoantibodies against PLA2R is …

Serum antibody and glomerular antigen of antiphospholipase A2 receptor in Chinese patients with idiopathic membranous nephropathy

Q Zhang, M Wu, Z Hu, X Liu, B Huang… - BioMed Research …, 2020 - Wiley Online Library
Background. M‐type phospholipase A2 receptor (PLA2R) is the first autoantigen responsible
for idiopathic membranous nephropathy (IMN). However, serum PLA2R antibody (PLA2R …

Prevalence of anti-phospholipase A2 receptor antibodies in Japanese patients with membranous nephropathy

S Akiyama, M Akiyama, E Imai, T Ozaki… - Clinical and …, 2015 - Springer
Background Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in
adults. Anti-M-type phospholipase A2 receptor (anti-PLA2R) antibodies are found in most …

Detection and monitoring PLA2R autoantibodies by LIPS in membranous nephropathy

PD Burbelo, LH Beck Jr, M Waldman - Journal of immunological methods, 2017 - Elsevier
Autoantibodies against the M-type phospholipase A 2 receptor (PLA 2 R) are specific
markers for primary membranous nephropathy (MN). Quantification of PLA 2 R …

The value of PLA2R antigen and IgG subclass staining relative to anti-PLA2R seropositivity in the differential diagnosis of membranous nephropathy

D Bajcsi, L Bitó, S Turkevi-Nagy, T Nyári, É Kemény… - BMC nephrology, 2023 - Springer
Background The diagnostic performance of PLA2R and IgG subclass staining of kidney
biopsies relative to anti-PLA2R seropositivity in the differentiation of primary and secondary …

[HTML][HTML] Anti-phospholipase A2 receptor antibody as a prognostic marker in patients with primary membranous nephropathy

EJ Song, KH Jeong, YA Yang, JH Lim… - Kidney research and …, 2018 - ncbi.nlm.nih.gov
Background Phospholipase A2 receptor (PLA2R) has been identified as a major
autoantigen in primary membranous nephropathy (MN). We evaluated the association …

Detection of PLA2R autoantibodies before the diagnosis of membranous nephropathy

PD Burbelo, M Joshi, A Chaturvedi… - Journal of the …, 2020 - journals.lww.com
Background Circulating serum autoantibodies against the M-type phospholipase A2
receptor (PLA2R-AB) are a key biomarker in the diagnosis and monitoring of primary …

Quantitative detection of anti-PLA2R antibodies targeting different epitopes and its clinical application in primary membranous nephropathy

Y Qin, Q Wu, H Sheng, T Li, X Liu, X Yang… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives This study aimed to establish time-resolved fluorescence immunoassays to
quantitatively detect the autoantibodies targeting different epitopes of M-type phospholipase …