Patient considerations and drug selection in the treatment of idiopathic pulmonary fibrosis

MA Trawinska, RD Rupesinghe… - Therapeutics and Clinical …, 2016 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease of unknown
cause. Approximately 5,000 people are diagnosed with IPF in the UK every year. People …

[HTML][HTML] Idiopathic pulmonary fibrosis: from clinical trials to real-life experiences

S Harari, A Caminati - European Respiratory Review, 2015 - Eur Respiratory Soc
Randomised controlled clinical trials are fundamental in medicine to develop new effective
drugs and new therapeutic regimens and are the strength of evidence-based medicine …

Idiopathic pulmonary fibrosis: clinically meaningful primary endpoints in phase 3 clinical trials

G Raghu, HR Collard, KJ Anstrom… - American journal of …, 2012 - atsjournals.org
Definitive evidence of clinical efficacy in a Phase 3 trial is best shown by a beneficial impact
on a clinically meaningful endpoint—that is, an endpoint that directly measures how a …

Idiopathic pulmonary fibrosis: current and future treatment options

HR Davies, L Richeldi - American Journal of Respiratory Medicine, 2002 - Springer
Idiopathic pulmonary fibrosis (IPF) is a chronic condition of unknown etiology with an
unfavorable outcome from progressively deteriorating respiratory function, leading ultimately …

Importance of early diagnosis and treatment in idiopathic pulmonary fibrosis

M Molina-Molina, M Aburto, O Acosta… - Expert Review of …, 2018 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a rare disease characterized by chronic, progressive,
and irreversible interstitial lung fibrosis of unknown cause [1, 2]. Main symptoms and signs …

Pharmacologic therapies for idiopathic pulmonary fibrosis, past and future

BS Staitieh, EA Renzoni, S Veeraraghavan - Annals of medicine, 2015 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a severe, progressive fibrotic disease of the lung of
unknown etiology that affects approximately 150,000 patients in the United States. It carries …

[HTML][HTML] Advances in the management of idiopathic pulmonary fibrosis

JH Ryu, CE Daniels - F1000 medicine reports, 2010 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a common form of interstitial lung disease and usually
results in progressive respiratory insufficiency and death. Steady progress has been made …

[HTML][HTML] Treatment of idiopathic pulmonary fibrosis: a network meta-analysis

B Rochwerg, B Neupane, Y Zhang, CC Garcia… - BMC medicine, 2016 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease associated with
high morbidity and mortality. Effective treatments for IPF are limited. Several recent studies …

Idiopathic pulmonary fibrosis: diagnosis and clinical manifestations

Y Nakamura, T Suda - Clinical Medicine Insights: Circulatory …, 2015 - journals.sagepub.com
Idiopathic pulmonary fibrosis (IPF) is a parenchymal lung disease characterized by
progressive interstitial fibrosis. The clinical course of IPF can be unpredictable and may be …

[HTML][HTML] A critical assessment of treatment options for idiopathic pulmonary fibrosis

NR Shah, P Noble, RM Jackson… - … vasculitis, and diffuse …, 2005 - ncbi.nlm.nih.gov
Background To date, no management approach has proven to be efficacious for the
treatment of idiopathic pulmonary fibrosis (IPF). Consequently, therapeutic options remain …