ABSTRACT BACKGROUND AND OBJECTIVES: In the past twenty years, the number of
deaths caused by opioid overdose has tripled in the United States. There is, in literature, a …

Objectives The rise in opioid prescriptions with a parallel increase in opioid use disorders
remains a significant challenge in some developed countries (opioid epidemic). However …

Background Global opioid consumption increased multifold post-2000, disproportionately in
high-income countries, with severe mortality/morbidity consequences. Latin America …

Background and objectives: There are few data in the literature characterizing the pattern of
analgesic use in Latin American countries, including Brazil. Little is known about the …

Objectives. To present and discuss recent patterns of prescription opioid sales throughout
Brazil. Methods. We graphed linear trends of opioid prescriptions sold from registered …

Background and objectives: There are few data in the literature characterizing the pattern of
analgesic use in Latin American countries, including Brazil. Little is known about the …

Prior studies on substance use in Brazil have not focused on opioid misuse, previously
thought to be nearly non-existent. This paper presents new findings on heroin and non …

Abstract Background In the United States of America, the increased use of opioids is
associated with serious risks, such as overdose, opioid use disorder and death. In Portugal …

BACKGROUND AND OBJECTIVES: Adequate opioid use in the short and long term, as well
as diagnosis, management of adverse effects, abuse and chemical dependence of such …

Opioids have incredible power to make lives better, as well as destroy them. After the latest
US opioid overuse crisis reported by the United Nations (UN) in 2017, several other …