Adaptor proteins of type VI secretion system effectors

D Unterweger, B Kostiuk, S Pukatzki - Trends in microbiology, 2017 - cell.com
Bacteria use the type VI secretion system (T6SS) to kill neighboring cells. One key feature of
the T6SS is the secretion of diverse effectors. Here, we discuss six publications that describe …

Structure of a bacterial Rhs effector exported by the type VI secretion system

P Günther, D Quentin, S Ahmad, K Sachar… - PLoS …, 2022 - journals.plos.org
The t ype VI s ecretion s ystem (T6SS) is a widespread protein export apparatus found in
Gram-negative bacteria. The majority of T6SSs deliver toxic effector proteins into competitor …

Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources?

F Boyer, G Fichant, J Berthod, Y Vandenbrouck, I Attree - BMC genomics, 2009 - Springer
Background The availability of hundreds of bacterial genomes allowed a comparative
genomic study of the Type VI Secretion System (T6SS), recently discovered as being …

ClpV recycles VipA/VipB tubules and prevents non‐productive tubule formation to ensure efficient type VI protein secretion

N Kapitein, G Bönemann, A Pietrosiuk… - Molecular …, 2013 - Wiley Online Library
The multicomponent type VI secretion system (T6SS) mediates the transport of effector
proteins by puncturing target membranes. T6SSs are suggested to form a contractile …

A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C‐terminal domain of the VgrG spike protein for delivery

N Flaugnatti, TTH Le, S Canaan… - Molecular …, 2016 - Wiley Online Library
The Type VI secretion system (T6SS) is a multiprotein machine that delivers protein effectors
in both prokaryotic and eukaryotic cells, allowing interbacterial competition and virulence …

Structure of the VipA/B type VI secretion complex suggests a contraction-state-specific recycling mechanism

S Kube, N Kapitein, T Zimniak, F Herzog, A Mogk… - Cell reports, 2014 - cell.com
The bacterial type VI secretion system is a multicomponent molecular machine directed
against eukaryotic host cells and competing bacteria. An intracellular contractile tubular …

Bacterial type VI secretion system (T6SS): an evolved molecular weapon with diverse functionality

RP Singh, K Kumari - Biotechnology letters, 2023 - Springer
Bacterial secretion systems are nanomolecular complexes that release a diverse set of
virulence factors/or proteins into its surrounding or translocate to their target host cells …

VgrG and PAAR proteins define distinct versions of a functional type VI secretion system

FR Cianfanelli, J Alcoforado Diniz, M Guo… - PLoS …, 2016 - journals.plos.org
The Type VI secretion system (T6SS) is widespread among bacterial pathogens and acts as
an effective weapon against competitor bacteria and eukaryotic hosts by delivering toxic …

Genetically distinct pathways guide effector export through the type VI secretion system

JC Whitney, CM Beck, YA Goo, AB Russell… - Molecular …, 2014 - Wiley Online Library
Bacterial secretion systems often employ molecular chaperones to recognize and facilitate
export of their substrates. Recent work demonstrated that a secreted component of the type …

Type VI secretion system: a modular toolkit for bacterial dominance

B Jana, D Salomon - Future microbiology, 2019 - Taylor & Francis
Bacteria use toxin delivery systems, such as the type VI secretion system (T6SS), to
antagonize competitors. The T6SS transports toxins, called effectors, directly into recipient …