Background Inflammatory cytokines including the IL-1 family, TNF-α and IL-6 mediate the
formation of thrombosis on the luminal surface of atherosclerotic plaques. Gene …

Aim To identify the associations of 19 single nucleotide polymorphisms (SNPs) in genes
involved in inflammation and endothelial function and carotid atherosclerosis with …

Despite recent advances in acute stroke therapy, stroke remains the leading cause of severe
disability and the third leading cause of death, after heart disease and cancer, in Western …

Background and Purpose—Proinflammatory genetic profiles, resulting from the combination
of single nucleotide polymorphisms in genes encoding inflammatory molecules, may …

Background and Purpose—If chronic inflammation plays a causal role in atherogenesis,
individuals with proinflammatory gene variants would be expected to develop more …

Inflammation has been associated with atherothrombotic stroke and recently with
cardioembolic stroke. Different genetic risk factors have been specifically associated with the …

Abstract Background: Single-nucleotide polymorphisms (SNPs) in inflammation-related
genes have been linked to an increased risk of ischemic stroke. Most of these SNP results …

Objective: A multigenetic pro-inflammatory profile may increase stroke risk. We investigated
whether a higher number of pro-inflammatory genetic variants are associated with ischaemic …

Inflammation is a key process linked to stroke both in terms of atherosclerosis, and in terms
of cerebral ischaemia. Secondary to endothelial injury, innate and acquired immune …

Background and Purpose—The genetic influence on carotid atherosclerotic plaque is mostly
unknown. This study examines the association between carotid plaque and single …