The ultimate hope of researchers and patients is a pathway to development of treatments for
osteoarthritis to modify the disease process in addition to the symptoms. However …

Understanding the molecular drivers and feedback loops of osteoarthritis (OA) may provide
future therapeutic strategies to modulate the disease progression. The current paradigm of …

Although osteoarthritis (OA) is the most common musculoskeletal condition that causes
significant health and social problems worldwide, its exact etiology is still unclear. With an …

Osteoarthritis (OA) is a painful and disabling disease that affects millions of people
worldwide. Symptom-alleviating treatments exist, although none with long-term efficacy …

[Frontiers in Bioscience 4, d762-771, October 15, 1999] 762 FUTURE DIRECTIONS FOR
RESEARCH AND TREATMENT OF OSTEOARTHRITIS Charl Page 1 [Frontiers in Bioscience 4 …

Osteoarthritis is a chronic degenerative disorder of the joint and represents one of the most
common diseases worldwide. Its prevalence and severity are increasing owing to aging of …

Osteoarthritis (OA) is the most common form of joint disease. Histopathologically, OA is
characterized by a progressive loss of articular cartilage, osteophyte formation, thickening of …

Osteoarthritis is often a progressive and disabling disease, which occurs in the setting of a
variety of risk factors–such as advancing age, obesity, and trauma–that conspire to incite a …

Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than
half of the over 65 population. In the past, OA was considered a wear and tear disease …

Osteoarthritis (OA), the most common of all arthritic conditions, is a social and financial
burden to all nations. The most recent research has significantly advanced our …