Osteoarthritis (OA) is a musculoskeletal disease characterized by progressive degeneration
of osteochondral tissues. Current treatment is restricted to the reduction of pain and loss of …

Arthritis is inflammation of the joints accompanied by osteochondral destruction. It can take
many forms, including osteoarthritis, rheumatoid arthritis, and psoriatic arthritis. These …

Osteoarthritis (OA) is a chronic, progressive degenerative whole joint disease that affects the
articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still …

It is increasingly recognized that the pathogenesis of cartilage degradation in osteoarthritis
(OA) is multifactorial and involves the interactions between cartilage and its surrounding …

Recent research in the field of osteoarthritis (OA) has focused on understanding the
underlying molecular and clinical phenotypes of the disease. This narrative review article …

OBJECTIVE: The purpose of this article is to review the current status of drug development
as it relates to both molecular targets and clinical trials for osteoarthritis (OA). METHODS: A …

Osteoarthritis (OA) is often a progressive and disabling disease resulting from a combination
of risk factors, including age, genetics, trauma, and knee alignment, as well as an imbalance …

Osteoarthritis (OA) is a chronic degenerative disease of the articular joint that involves both
bone and cartilage degenerative changes. An engineered osteochondral tissue within …

A sharp rise in osteoarthritis (OA) incidence is expected as over 25% of world population
ages in the coming decade. Although OA is considered a degenerative disease, mounting …

Osteoarthritis (OA) is an age-related condition and the leading cause of pain, disability and
shortening of adult working life in the UK. The incidence of OA increases with age, with 25 …