[HTML][HTML] Addressing benefits, risks and consent in next generation sequencing studies
R Meller - Journal of clinical research & bioethics, 2015 - ncbi.nlm.nih.gov
The sequencing of the human genome and technological advances in DNA sequencing
have led to a revolution with respect to DNA sequencing and its potential to diagnose …
have led to a revolution with respect to DNA sequencing and its potential to diagnose …
Ethical Challenges to Next-Generation Sequencing
S Solomon - Clinical Genomics, 2015 - Elsevier
Today, we are on the cusp of a revolution in healthcare delivery where clinicians will be able
to access patients' genetic information cheaply, quickly, and entirely. As the much …
to access patients' genetic information cheaply, quickly, and entirely. As the much …
Return of results in genomic research using large-scale or whole genome sequencing: toward a new normal
SM Wolf, RC Green - Annual Review of Genomics and Human …, 2023 - annualreviews.org
Genome sequencing is increasingly used in research and integrated into clinical care. In the
research domain, large-scale analyses, including whole genome sequencing with variant …
research domain, large-scale analyses, including whole genome sequencing with variant …
Privacy and ethical challenges in next-generation sequencing
N Martinez-Martin, D Magnus - Expert review of precision medicine …, 2019 - Taylor & Francis
Introduction: Next-generation sequencing (NGS) is expected to revolutionize health care.
NGS allows for sequencing of the whole genome more cheaply and quickly than previous …
NGS allows for sequencing of the whole genome more cheaply and quickly than previous …
Ethical issues in medical-sequencing research: implications of genotype–phenotype studies for individuals and populations
MW Foster, RR Sharp - Human molecular genetics, 2006 - academic.oup.com
Advances and declining costs in sequencing technology will result in increasing number of
studies with individual sequence data linked to phenotypic information, which has been …
studies with individual sequence data linked to phenotypic information, which has been …
Next generation DNA sequencing: always allow an opt out
AL Bredenoord, RM Bijlsma… - The American Journal of …, 2015 - Taylor & Francis
RETURN OF RESULTS: AN ONGOING DEBATE With the rapid development of next-
generation sequencing (NGS) technologies, among them whole exome and whole genome …
generation sequencing (NGS) technologies, among them whole exome and whole genome …
Revealing the results of whole-genome sequencing and whole-exome sequencing in research and clinical investigations: some ethical issues
N Hallowell, A Hall, C Alberg, R Zimmern - Journal of Medical Ethics, 2015 - jme.bmj.com
The introduction of new sequencing technologies whole-genome sequencing (WGS) and
whole-exome sequencing (WES) that are much less finely targeted than previous genetic …
whole-exome sequencing (WES) that are much less finely targeted than previous genetic …
The $1000 genome: ethical and legal issues in whole genome sequencing of individuals
JA Robertson - American Journal of Bioethics, 2003 - Taylor & Francis
Progress in gene sequencing could make rapid whole genome sequencing of individuals
affordable to millions of persons and useful for many purposes in a future era of genomic …
affordable to millions of persons and useful for many purposes in a future era of genomic …
HeLa Sequencing and Genomic Privacy: The Next Chapter
BJ Andrews, T DePellegrin - G3: Genes, Genomes, Genetics, 2013 - academic.oup.com
This month's issue of G3: Genes| Genomes| Genetics features the article “The Genomic and
Transcriptomic Landscape of a HeLa Cell Line” by Landry et al., and presents a genomic …
Transcriptomic Landscape of a HeLa Cell Line” by Landry et al., and presents a genomic …
Mapping the ethics of translational genomics: situating return of results and navigating the research-clinical divide
SM Wolf, W Burke, BA Koenig - Journal of Law, Medicine & Ethics, 2015 - cambridge.org
Research on the use of genome and exome sequencing for diagnosis, identification of
potential therapies, precision prescribing of pharmaceuticals, and identification of disease …
potential therapies, precision prescribing of pharmaceuticals, and identification of disease …