Background—Histone deacetylase 3 (HDAC3) is known to play a crucial role in the
differentiation of endothelial progenitors. The role of HDAC3 in mature endothelial cells …

Development and homeostasis of the cardiovascular system require intimate interactions
between endothelial and smooth muscle cells, which form a seamless circulatory network …

Global inhibition of class I and II histone deacetylases (HDACs) impairs angiogenesis.
Herein, we have undertaken the identification of the specific HDAC (s) with activity that is …

The histone deacetylases (HDACs) are a family of enzymes that catalyse lysine
deacetylation of both histone and non-histone proteins. Here, we review, summarize, and …

Angiogenesis, a process by which the preexisting blood vasculature gives rise to new
capillary vessels, is associated with a variety of physiologic and pathologic conditions …

Histone deacetylases (HDACs) deacetylate histones and non‐histone proteins, thereby
affecting protein activity and gene expression. The regulation and function of the cytoplasmic …

A total number of 18 different isoforms of histone deacetylases (HDACs) which were
categorized into 4 classes have been identified in human. HDAC3 is categorized as class I …

Objective—Histone acetylation/deacetylation plays an important role in the control of gene
expression, tissue growth, and development. In particular, histone deacetylases 7 (HDAC7) …

Abstract Class IIa histone deacetylases (HDACs) are signal-responsive regulators of gene
expression involved in vascular homeostasis. To investigate the differential role of class IIa …

Endothelial-mesenchymal transition (EndMT) is associated with various cardiovascular
diseases and in particular with atherosclerosis and plaque instability. However, the …