Cancer stem cell vaccination confers significant antitumor immunity
N Ning, Q Pan, F Zheng, S Teitz-Tennenbaum… - Cancer research, 2012 - AACR
Most studies of cancer stem cells (CSC) involve the inoculation of cells from human tumors
into immunosuppressed mice, preventing an assessment on the immunologic interactions …
into immunosuppressed mice, preventing an assessment on the immunologic interactions …
Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells
L Lu, H Tao, AE Chang, Y Hu, G Shu, Q Chen… - …, 2015 - Taylor & Francis
The inability to target cancer stem cells (CSC) may be a significant factor contributing to
treatment failure. We have developed a strategy to target the CSC populations in melanoma …
treatment failure. We have developed a strategy to target the CSC populations in melanoma …
Cancer stem cells: regulation programs, immunological properties and immunotherapy
It is becoming increasingly clear that virtually all types of human cancers harbor a small
population of stem-like cancer cells (ie, cancer stem cells, CSCs). These CSCs preexist in …
population of stem-like cancer cells (ie, cancer stem cells, CSCs). These CSCs preexist in …
Concise review: targeting cancer stem cells using immunologic approaches
Q Pan, Q Li, S Liu, N Ning, X Zhang, Y Xu… - Stem …, 2015 - academic.oup.com
Cancer stem cells (CSCs) represent a small subset of tumor cells which have the ability to
self-renew and generate the diverse cells that comprise the tumor bulk. They are …
self-renew and generate the diverse cells that comprise the tumor bulk. They are …
Cancer stem cell immunology and immunotherapy: Harnessing the immune system against cancer's source
R Ruiu, L Tarone, V Rolih, G Barutello, E Bolli… - Progress in molecular …, 2019 - Elsevier
Despite recent advances in diagnosis and therapy having improved cancer outcome, many
patients still do not respond to treatments, resulting in the progression or relapse of the …
patients still do not respond to treatments, resulting in the progression or relapse of the …
Antigen-specific T-cell response from dendritic cell vaccination using cancer stem-like cell-associated antigens
Q Xu, G Liu, X Yuan, M Xu, H Wang, J Ji, B Konda… - Stem …, 2009 - academic.oup.com
Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor, with current
treatment remaining palliative. Immunotherapies harness the body's own immune system to …
treatment remaining palliative. Immunotherapies harness the body's own immune system to …
Immune responses to human cancer stem‐like cells/cancer‐initiating cells
Y Hirohashi, T Torigoe, T Tsukahara… - Cancer …, 2016 - Wiley Online Library
Cancer stem‐like cells (CSC)/cancer‐initiating cells (CIC) are defined as minor
subpopulations of cancer cells that are endowed with properties of higher tumor‐initiating …
subpopulations of cancer cells that are endowed with properties of higher tumor‐initiating …
Recent advances in cancer stem cell-targeted immunotherapy
N Badrinath, SY Yoo - Cancers, 2019 - mdpi.com
Cancer stem cells (CSCs) are one of the reasons for the relapse of cancer cells and
metastasis. They have drug resistance against most chemotherapeutic agents. CSCs are …
metastasis. They have drug resistance against most chemotherapeutic agents. CSCs are …
The role of cancer stem cells in the modulation of anti-tumor immune responses
C Maccalli, KI Rasul, M Elawad, S Ferrone - Seminars in cancer biology, 2018 - Elsevier
Tumor lesions comprise multiple subpopulations of cells including those endowed with
“stemness” properties. The latter cells are responsible of tumor initiation, metastasis …
“stemness” properties. The latter cells are responsible of tumor initiation, metastasis …
Dendritic cell based immunotherapy using tumor stem cells mediates potent antitumor immune responses
Cancer stem cells (CSCs) are demonstrated to be usually less sensitive to conventional
methods of cancer therapies, resulting in tumor relapse. It is well-known that an ideal …
methods of cancer therapies, resulting in tumor relapse. It is well-known that an ideal …