Background Heterogeneous airway narrowing and closure are characteristics of asthma.
However, they have never been quantified by direct measurements of parallel sister airways …

Bronchial wall area percent (WA%= 100× wall area/total bronchial cross sectional area) is a
standard computed tomographic (CT) measure of central airway morphology utilized in …

Airway remodeling in asthma and chronic obstructive pulmonary disease (COPD) results in
thickening of bronchial walls and may affect lung function. In the present study we set out to …

Asthma and chronic obstructive pulmonary disease (COPD) are characterised by airflow
obstruction, airway remodelling (measurable structural change) and inflammation. The …

Rationale: Our understanding of how airway remodeling affects regional airway elastic
properties is limited due to technical difficulties in quantitatively measuring dynamic, in vivo …

Background In CT scans of smokers with COPD, the subsegmental airway wall area percent
(WA%) is greater and more strongly correlated with FEV 1% predicted than WA% obtained …

Objective: It is not well known whether there is heterogeneity in the airway dimensions at
different anatomic locations in individual patients with COPD. The first objective was to …

Background CT scan measures of emphysema and airway disease have been correlated
with lung function in cohorts of subjects with a range of COPD severity. The contribution of …

Background Quantitative computed tomographic (QCT) biomarkers of airway morphology
hold potential for understanding and monitoring regional airway remodeling in asthmatic …

BACKGROUND: COPD patients have varying degrees of airways disease and emphysema.
CT scanning can differentiate these pathological subtypes. We evaluated airway dimensions …