Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
limitation caused by emphysema and/or airway narrowing. Computed tomography has been …

Purpose: To prospectively validate the ability of customized three-dimensional (3D) software
to enable bronchial tree skeletonization, orthogonal reconstruction of the main bronchial …

Background An increase in airway caliber (airway distensibility) with lung inflation is
attenuated in COPD. Furthermore, some subjects have a decrease in airway caliber with …

PURPOSE: To design and validate a dedicated software tool to measure airway dimensions
on thin-section computed tomographic (CT) images and to use the tool to prospectively …

Rationale and Objectives To analyze airway dimensions throughout the bronchial tree in
severe asthmatic patients using multidetector row computed tomography (MDCT) focusing …

Background Chronic cough, which may be of asthmatic or nonasthmatic origin, is an
important clinical issue. Airway inflammation, and remodeling demonstrated by …

The aim of this study was to examine the relationship between the structural changes in
large and small airways in asymptomatic asthmatics quantified by high-resolution computed …

Chronic obstructive pulmonary disease may cause airway remodeling, and small airways
are the mostly likely site of associated airway flow obstruction. Detecting and quantifying …

Background Partial volume averaging and tilt relative to the scan plane on transverse
images limit the accuracy of airway wall thickness measurements on CT scan, confounding …

Rationale: Airway remodeling in chronic obstructive pulmonary disease (COPD) is due to
luminal narrowing and/or loss of airways. Existing computed tomographic metrics of airway …