The discovery that aggregated transactive response DNA-binding protein 43 kDa (TDP-43)
is the major component of pathological ubiquitinated inclusions in amyotrophic lateral …

Ever since the significance of pathological 43-kDa transactivating responsive sequence
DNA-binding protein (TDP-43) for human disease has been recognized in amyotrophic …

The rapid confirmation of the initial report by Neumann et al.(Science 314: 130–133, 2006)
that transactive response (TAR)-DNA-binding protein 43 (TDP-43) is the major disease …

The identification of TDP-43 as the major component of the pathologic inclusions in most
forms of sporadic and familial frontotemporal lobar degeneration with ubiquitin-positive …

In this review, we summarize recent advances in understanding frontotemporal lobar
degeneration (FTLD), amyotrophic lateral sclerosis (ALS) and related neurodegenerative …

Transactive response DNA-binding protein 43 kDa (TDP-43) was identified as a major
disease-associated component in the brain of patients with amyotrophic lateral sclerosis …

TDP-43 is the primary or secondary pathological hallmark of neurodegenerative diseases,
such as amyotrophic lateral sclerosis, half of frontotemporal dementia cases, and limbic age …

Pathological 43-kDa transactive response sequence DNA-binding protein (TDP-43) has
been recognized as the major disease protein in amyotrophic lateral sclerosis (ALS) …

Abstract TAR DNA-binding protein-43 (TDP-43) accumulation is the primary pathology
underlying several neurodegenerative diseases. Charting the progression and …

Aggregation of misfolded TAR DNA-binding protein 43 (TDP-43) is a striking hallmark of
neurodegenerative processes that are observed in several neurological disorders, and in …