Examining cocaine use reductions and long-term outcomes in two clinical trials of continuing care for cocaine dependence

VR Votaw, FR Tuchman, CR Roos, HM Hebden… - Journal of Substance …, 2024 - Elsevier
Background There is a need to identify clinically meaningful non-abstinent endpoints for
cocaine use disorder (CUD) clinical trials. In this study, we sought to replicate and extend …

[HTML][HTML] Measuring outcome in the treatment of cocaine dependence

P Crits-Christoph, R Gallop, MBC Gibbons… - Journal of alcoholism …, 2013 - ncbi.nlm.nih.gov
Background Little in known about the extent to which outcome measures used in studies of
the treatment of cocaine dependence are associated with longer-term use and with broader …

Clinical validation of reduction in cocaine frequency level as an endpoint in clinical trials for cocaine use disorder

CR Roos, C Nich, CJ Mun, TA Babuscio… - Drug and alcohol …, 2019 - Elsevier
Background Despite calls for non-abstinence endpoints in randomized clinical trials (RCTs)
for cocaine use disorder, there is a lack of data validating non-abstinence endpoints. We …

Patterns of cocaine use during treatment: associations with baseline characteristics and follow-up functioning

CR Roos, C Nich, CJ Mun, J Mendonca… - Journal of studies on …, 2019 - jsad.com
Objective: Abstinence outcomes are typically prioritized in the treatment of cocaine use
disorder while ignoring patterns of low-frequency cocaine use. This study examined patterns …

What happens in treatment doesn't stay in treatment: Cocaine abstinence during treatment is associated with fewer problems at follow-up.

BD Kiluk, C Nich, K Witkiewitz… - Journal of Consulting …, 2014 - psycnet.apa.org
Objective: Cocaine users often present to treatment with a multitude of problems typically
considered addiction related; however, there is little evidence that reductions in cocaine use …

Short and long-term improvements in psychiatric symptomatology to validate clinically meaningful treatment outcomes for cocaine use disorders

AQC Miguel, BD Kiluk, TA Babuscio, C Nich… - Drug and Alcohol …, 2019 - Elsevier
Background Substantial efforts have been made to identify clinically meaningful non-
abstinence cocaine use outcomes by establishing associations between targeted drug use …

Factors in sustained recovery from cocaine dependence

JR McKay, D Van Horn, L Rennert, M Drapkin… - Journal of substance …, 2013 - Elsevier
The goal was to identify factors that predicted sustained cocaine abstinence and transitions
from cocaine use to abstinence over 24months. Data from baseline assessments and …

One-year follow-up of psychotherapy and pharmacotherapy for cocaine dependence: Delayed emergence of psychotherapy effects

KM Carroll, BJ Rounsaville, C Nich… - Archives of general …, 1994 - jamanetwork.com
Background: Neither the durability of brief ambulatory treatments for cocaine dependence
nor the relative ability of psychotherapy vs pharmacotherapy to effect lasting change has …

Longitudinal treatment effects among cocaine users: a growth curve modeling approach

CP Chou, YI Hser, MD Anglin - Substance use & misuse, 2003 - Taylor & Francis
This study examined longitudinal treatment effects among cocaine users. The study
examined a sample of 371 cocaine users screened from arrestees in jails and from patients …

Decreased cocaine demand following contingency management treatment

JH Yoon, R Suchting, C de Dios, JN Vincent… - Drug and Alcohol …, 2021 - Elsevier
A hypothetical cocaine purchasing task (CocPT) was used to assess changes in cocaine
demand in the context of contingency management (CM) treatment for cocaine use disorder …