Mitochondrial and cellular heme-dependent proteins as targets for the bioactive function of the heme oxygenase/carbon monoxide system
M Desmard, J Boczkowski, J Poderoso… - Antioxidants & Redox …, 2007 - liebertpub.com
The toxic effect of high concentrations of CO gas in living organisms is coherently typified at
biochemical levels by the high affinity of CO for hemoglobin and cytochromes, heme …
biochemical levels by the high affinity of CO for hemoglobin and cytochromes, heme …
Heme oxygenase/carbon monoxide signaling path-ways: Regulation and functional significance
SW Ryter, LE Otterbein, D Morse, AMK Choi - Oxygen/Nitrogen Radicals …, 2002 - Springer
Carbon monoxide (CO), a gaseous second messenger, arises in biological systems during
the oxidative catabolism of heme by the heme oxygenase (HO) enzymes. HO exists as …
the oxidative catabolism of heme by the heme oxygenase (HO) enzymes. HO exists as …
[HTML][HTML] Endogenous carbon monoxide signaling modulates mitochondrial function and intracellular glucose utilization: impact of the heme oxygenase substrate …
D Stucki, J Steinhausen, P Westhoff, H Krahl… - Antioxidants, 2020 - mdpi.com
Stress-inducible heme oxygenase-1 (HO-1) catalyzes the oxidative cleavage of heme
yielding biliverdin, ferrous iron, and carbon monoxide (CO). Heme oxygenase activity has …
yielding biliverdin, ferrous iron, and carbon monoxide (CO). Heme oxygenase activity has …
Biological signaling by carbon monoxide and carbon monoxide-releasing molecules
R Motterlini, R Foresti - American Journal of Physiology …, 2017 - journals.physiology.org
Carbon monoxide (CO) is continuously produced in mammalian cells during the
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …
Carbon monoxide in biology and medicine
SW Ryter, LE Otterbein - Bioessays, 2004 - Wiley Online Library
Carbon monoxide (CO), a product of organic oxidation processes, arises in vivo during
cellular metabolism, most notably heme degradation. CO binds to the heme iron of most …
cellular metabolism, most notably heme degradation. CO binds to the heme iron of most …
Carbon monoxide, reactive oxygen signaling, and oxidative stress
CA Piantadosi - Free Radical Biology and Medicine, 2008 - Elsevier
The ubiquitous gas, carbon monoxide (CO), is of substantial biological importance, but apart
from its affinity for reduced transition metals, particularly heme-iron, it is surprisingly …
from its affinity for reduced transition metals, particularly heme-iron, it is surprisingly …
[HTML][HTML] Friend or foe? Carbon monoxide and the mitochondria
N Schallner, LE Otterbein - Frontiers in Physiology, 2015 - frontiersin.org
The longstanding perception of the gas carbon monoxide (CO) as an odorless and colorless
“silent killer” began to attract the attention of the public with the arrival of the industrial age in …
“silent killer” began to attract the attention of the public with the arrival of the industrial age in …
Biological chemistry of carbon monoxide
CA Piantadosi - Antioxidants and Redox Signaling, 2002 - liebertpub.com
Carbon monoxide (CO) has many effects in biology due to its complex biochemical activities.
These actions of CO depend primarily on its ability to bind heme proteins (Hp) and to inhibit …
These actions of CO depend primarily on its ability to bind heme proteins (Hp) and to inhibit …
The role of carbon monoxide as a gasotransmitter in cardiovascular and metabolic regulation
Carbon monoxide (CO) is produced endogenously through the oxidative catabolism of
heme by heme oxygenase (HO). First described as a putative neuronal signaling …
heme by heme oxygenase (HO). First described as a putative neuronal signaling …
Heme oxygenase and carbon monoxide initiate homeostatic signaling
M Bilban, A Haschemi, B Wegiel, BY Chin… - Journal of Molecular …, 2008 - Springer
Carbon monoxide (CO), a gaseous second messenger, arises in biological systems during
the oxidative catabolism of heme by the heme oxygenase (HO) enzymes. Many biological …
the oxidative catabolism of heme by the heme oxygenase (HO) enzymes. Many biological …
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