Chronic hypoxia aggravates monocrotaline-induced pulmonary arterial hypertension: a rodent relevant model to the human severe form of the disease
Pulmonary arterial hypertension (PAH) is a severe form of pulmonary hypertension that
combines multiple alterations of pulmonary arteries, including, in particular, thrombotic and …
combines multiple alterations of pulmonary arteries, including, in particular, thrombotic and …
The monocrotaline model of pulmonary hypertension in perspective
JG Gomez-Arroyo, L Farkas… - … of Physiology-Lung …, 2012 - journals.physiology.org
Severe forms of pulmonary arterial hypertension (PAH) are characterized by various
degrees of remodeling of the pulmonary arterial vessels, which increases the pulmonary …
degrees of remodeling of the pulmonary arterial vessels, which increases the pulmonary …
Development and characterization of an animal model of severe pulmonary arterial hypertension
Y Morimatsu, N Sakashita, Y Komohara… - Journal of vascular …, 2011 - karger.com
Pulmonary arterial hypertension (PAH) is a serious pathological phenomenon with poor
prognosis, which is associated with morphological as well as hemodynamic alteration of the …
prognosis, which is associated with morphological as well as hemodynamic alteration of the …
Pulmonary artery hypertension model in rats by monocrotaline administration
Pulmonary arterial hypertension (PAH) is a syndrome characterized by pulmonary vascular
remodeling and vasoconstriction, leading to increased pulmonary vascular resistance, right …
remodeling and vasoconstriction, leading to increased pulmonary vascular resistance, right …
Exploring the monocrotaline animal model for the study of pulmonary arterial hypertension: A network approach
Pulmonary arterial hypertension (PAH) is responsible for the premature death mainly
because of progressive and severe heart failure. This disease is characterized by increased …
because of progressive and severe heart failure. This disease is characterized by increased …
Rodent models of group 1 pulmonary hypertension
Abstract World Health Organization category 1 pulmonary hypertension (PH) is a
heterogeneous syndrome in which PH originates in the small pulmonary arteries and is …
heterogeneous syndrome in which PH originates in the small pulmonary arteries and is …
Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure
KR Stenmark, B Meyrick, N Galie… - … of Physiology-Lung …, 2009 - journals.physiology.org
At present, six groups of chronic pulmonary hypertension (PH) are described. Among these,
group 1 (and 1′) comprises a group of diverse diseases termed pulmonary arterial …
group 1 (and 1′) comprises a group of diverse diseases termed pulmonary arterial …
Advancing therapy for pulmonary arterial hypertension: can animal models help?
IM Robbins - American journal of respiratory and critical care …, 2004 - atsjournals.org
Pulmonary arterial hypertension (PAH) is a disorder predominantly affecting the small
pulmonary arteries. It can occur without an identifiable cause, primary pulmonary …
pulmonary arteries. It can occur without an identifiable cause, primary pulmonary …
Monocrotaline‐Induced Pulmonary Hypertension in Wistar Rats
M Rey, P Hess, M Clozel - Current Protocols in Pharmacology, 2009 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a debilitating and often fatal disease characterized
by a progressive increase in pulmonary vascular resistance that leads to right ventricular …
by a progressive increase in pulmonary vascular resistance that leads to right ventricular …
Animal models of pulmonary arterial hypertension
R Naeije, L Dewachter - Revue des maladies respiratoires, 2007 - europepmc.org
INTRODUCTION: Pulmonary arterial hypertension (PAH) is a rare syndrome of fatigue and
dyspnoea, caused by increased pulmonary vascular resistance and right heart failure …
dyspnoea, caused by increased pulmonary vascular resistance and right heart failure …