The peroxisome biogenesis factors Pex4p, Pex22p, Pex1p, and Pex6p act in the terminal steps of peroxisomal matrix protein import
CS Collins, JE Kalish, JC Morrell… - … and cellular biology, 2000 - Taylor & Francis
Peroxisomes are independent organelles found in virtually all eukaryotic cells. Genetic
studies have identified more than 20 PEX genes that are required for peroxisome …
studies have identified more than 20 PEX genes that are required for peroxisome …
Ubiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein …
JAKW Kiel, K Emmrich, HE Meyer, WH Kunau - Journal of Biological …, 2005 - ASBMB
PEX genes encode proteins (peroxins) that are required for the biogenesis of peroxisomes.
One of these peroxins, Pex5p, is the receptor for matrix proteins with a type 1 peroxisomal …
One of these peroxins, Pex5p, is the receptor for matrix proteins with a type 1 peroxisomal …
Pex17p of Saccharomyces cerevisiae Is a Novel Peroxin and Component of the Peroxisomal Protein Translocation Machinery
The Saccharomyces cerevisiae pex17-1 mutant was isolated from a screen to identify
mutants defective in peroxisome biogenesis. pex17-1 and pex17 null mutants fail to import …
mutants defective in peroxisome biogenesis. pex17-1 and pex17 null mutants fail to import …
Peroxisome Remnants in pex3Δ Cells and the Requirement of Pex3p for Interactions Between the Peroxisomal Docking and Translocation Subcomplexes
PP Hazra, I Suriapranata, WB Snyder, S Subramani - Traffic, 2002 - Wiley Online Library
During peroxisomal matrix protein import, the peroxisomal targeting signal receptors
recognize cargo in the cytosol and interact with docking and translocation subcomplexes on …
recognize cargo in the cytosol and interact with docking and translocation subcomplexes on …
A new yeast peroxin, Pex36, a functional homolog of mammalian PEX16, functions in the ER-to-peroxisome traffic of peroxisomal membrane proteins
Peroxisomal membrane proteins (PMPs) traffic to peroxisomes by two mechanisms: direct
insertion from the cytosol into the peroxisomal membrane and indirect trafficking to …
insertion from the cytosol into the peroxisomal membrane and indirect trafficking to …
[HTML][HTML] Peroxisome membrane biogenesis: the stage is set
W Schliebs, WH Kunau - Current biology, 2004 - cell.com
Pex3p and Pex19p are key players in the post-translational import of peroxisomal
membrane proteins. New data suggest that these peroxins act in tandem, Pex19p as a …
membrane proteins. New data suggest that these peroxins act in tandem, Pex19p as a …
Pex18p is constitutively degraded during peroxisome biogenesis
PE Purdue, PB Lazarow - Journal of Biological Chemistry, 2001 - ASBMB
Pex18p and Pex21p are structurally related yeast peroxins (proteins required for
peroxisome biogenesis) that are partially redundant in function. One or the other is essential …
peroxisome biogenesis) that are partially redundant in function. One or the other is essential …
The N-domain of Pex22p can functionally replace the Pex3p N-domain in targeting and peroxisome formation
A Halbach, R Rucktäschel, H Rottensteiner… - Journal of Biological …, 2009 - ASBMB
Pex3p is a central component of the import machinery for peroxisomal membrane proteins
(PMPs) that can reach peroxisomes via the endoplasmic reticulum (ER) and even trigger de …
(PMPs) that can reach peroxisomes via the endoplasmic reticulum (ER) and even trigger de …
[HTML][HTML] Peroxisomal protein translocation
W Girzalsky, D Saffian, R Erdmann - Biochimica et Biophysica Acta (BBA) …, 2010 - Elsevier
Peroxisomes perform a wide variety of metabolic processes in eukaryotic organisms.
Mutations that affect peroxisome function or formation have profound phenotypic …
Mutations that affect peroxisome function or formation have profound phenotypic …
The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p-and Pex16p-dependent pathway
T Matsuzaki, Y Fujiki - The Journal of cell biology, 2008 - rupress.org
Two distinct pathways have recently been proposed for the import of peroxisomal membrane
proteins (PMPs): a Pex19p-and Pex3p-dependent class I pathway and a Pex19p-and Pex3p …
proteins (PMPs): a Pex19p-and Pex3p-dependent class I pathway and a Pex19p-and Pex3p …