The TOPAS Monte Carlo (MC) system is used in radiation therapy and medical imaging
research, having played a significant role in making Monte Carlo simulations widely …

Purpose This paper covers recent developments and applications of the TOPAS TOol for
PArticle Simulation and presents the approaches used to disseminate TOPAS. Materials and …

Simulation of water radiolysis and the subsequent chemistry provides important information
on the effect of ionizing radiation on biological material. The Geant4 Monte Carlo toolkit has …

The cellular response to ionizing radiation continues to be of significant research interest in
cancer radiotherapy, and DNA is recognized as the critical target for most of the biologic …

Computational simulations offer a powerful tool for quantitatively investigating radiation
interactions with biological tissue and can help bridge the gap between physics, chemistry …

Computational simulations, such as Monte Carlo track structure simulations, offer a powerful
tool for quantitatively investigating radiation interactions within cells. The modelling of the …

Purpose The simulation of individual particle tracks and the chemical stage following water
radiolysis in biological tissue is an effective means of improving our knowledge of the …

Simple Summary A brief description of the methodologies to simulate ionizing radiation
transport in biologically relevant matter is presented. Emphasis is given to the physical …

Ionising radiation induced DNA damage and subsequent biological responses to it depend
on the radiation's track-structure and its energy loss distribution pattern. To investigate the …

Our understanding of radiation-induced cellular damage has greatly improved over the past
few decades. Despite this progress, there are still many obstacles to fully understand how …