Naïve T cells are multipotential precursors that differentiate into various effector subsets,
such as T helper type 1 (Th1) and Th2 cells, which are characterized by their distinct …

Abstract IL-17A-producing CD4+ T helper cells (Th17) are crucial for the development of
inflammatory and autoimmune diseases and thus are exploited for clinical immunotherapies …

Th17 cells are generally considered to be positive regulators of immune responses because
they produce pro-inflammatory cytokines, including IL-17A, IL-17F, and IL-22. Cytokine …

T helper (TH) cells can assume different phenotypes characterized by the secretion of
distinct effector molecules. Interferon-γ producing TH1 and IL-4 producing TH2 cells have …

Abstract T helper 17 (Th17), a distinct subset of CD4+ T cells with IL-17 as their major
cytokine, orchestrate the pathogenesis of inflammatory and autoimmune diseases …

CD4+ T helper cells are classical but constantly reinterpreted T-cell subset, playing critical
roles in a diverse range of inflammatory responses or diseases. Depending on the cytokines …

Th17 cells are a new subset of CD4+ T cells involved in the clearance of extracellular
pathogens and fungi. Accumulating evidence suggests that Th17 cells and their signature …

Abstract OTHER ARTICLES PUBLISHED IN THIS MINI-REVIEW SERIES ON Th17 CELLS
Induction of interleukin-17 production by regulatory T cells. Clin Exp Immunol 2009; doi …

IL-17-producing T cells have recently been classified as a new effector T-cell subset, termed
Th17, which is distinct from Th1, Th2 and Treg subsets. There has been much progress in …

Classically naïve CD4+ have been thought to differentiate into two possible lineages, T
helper 1 (Th1) or T helper 2 (Th2) cells. Within this paradigm the pathogenesis of …