Biomolecular condensation via liquid–liquid phase separation (LLPS) of intrinsically
disordered proteins/regions (IDPs/IDRs), with and without nucleic acids, has drawn …

Liquid–liquid phase separation (LLPS) of proteins into biomolecular condensates has
emerged as a fundamental principle underpinning cellular function and malfunction. Indeed …

Aggregation of the microtubule-associated protein tau plays a major role in Alzheimer's
disease and several other neurodegenerative disorders. An exciting recent development is …

Formation of membrane-less organelles via liquid-liquid phase separation is one way cells
meet the biological requirement for spatiotemporal regulation of cellular components and …

The liquid–liquid phase separation (LLPS) of Tau has been postulated to play a role in
modulating the aggregation property of Tau, a process known to be critically associated with …

Metabolic reactions within cells occur in various isolated compartments with or without
borders, the latter being known as membrane-less organelles (MLOs). The MLOs show …

Cellular condensation of intrinsically disordered proteins (IDPs) through liquid–liquid phase
separation (LLPS) allows dynamic compartmentalization and regulation of biological …

Liquid–liquid phase separation (LLPS) of proteins enables the formation of non-membrane-
bound organelles in cells and is associated with cancer and neurodegeneration. Little is …

Recent studies have indicated that tau, a protein involved in Alzheimer's disease and other
neurodegenerative disorders, has a propensity to undergo liquid–liquid phase separation …

Neurodegenerative diseases are associated with the pathological deposition of many
different intrinsically disordered proteins or proteins with intrinsically disordered regions …