Cingulate island sign temporally changes in dementia with Lewy bodies

T Iizuka, R Iizuka, M Kameyama - Scientific Reports, 2017 - nature.com
The cingulate island sign (CIS) that reflects sparing of the posterior cingulate cortex (PCC)
relative to the precuneus plus cuneus on FDG-PET and brain perfusion SPECT, has been …

Dementia with Lewy bodies: basis of cingulate island sign

J Graff-Radford, ME Murray, VJ Lowe, BF Boeve… - Neurology, 2014 - AAN Enterprises
Objectives: To investigate clinical, imaging, and pathologic associations of the cingulate
island sign (CIS) in dementia with Lewy bodies (DLB). Methods: We retrospectively …

Neuropathological changes in dementia with Lewy bodies and the cingulate island sign

L Patterson, MJ Firbank, SJ Colloby… - … of Neuropathology & …, 2019 - academic.oup.com
The cingulate island sign (CIS) refers to the relative sparing of metabolism in the posterior
cingulate cortex (PCC) and represents an important biomarker in distinguishing dementia …

[HTML][HTML] A visual rating scale for cingulate island sign on 18F-FDG-PET to differentiate dementia with Lewy bodies and Alzheimer's disease

L Gjerum, KS Frederiksen, OM Henriksen, I Law… - Journal of the …, 2020 - Elsevier
Valid diagnosis of dementia with Lewy bodies (DLB) is essential to establish appropriate
treatment and care. However, the diagnostic accuracy is complicated by clinical and …

Cingulate island sign on FDG-PET is associated with medial temporal lobe atrophy in dementia with Lewy bodies

T Iizuka, M Kameyama - Annals of nuclear medicine, 2016 - Springer
Objective The cingulate island sign (CIS), which refers to sparing of the posterior cingulate
relative to the precuneus and cuneus, has been proposed as an FDG-PET imaging feature …

The cingulate island sign on FDG‐PET vs. IMP‐SPECT to assess mild cognitive impairment in Alzheimer's disease vs. dementia with Lewy bodies

Y Chiba, H Fujishiro, E Iseki… - Journal of …, 2019 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE The cingulate island sign (CIS) on 18F‐
fluorodeoxyglucose positron emission tomography (FDG‐PET); ie, the relative preservation …

The cingulate island sign within early Alzheimer's disease-specific hypoperfusion volumes of interest is useful for differentiating Alzheimer's disease from dementia …

E Imabayashi, K Yokoyama, T Tsukamoto, D Sone… - EJNMMI research, 2016 - Springer
Background In addition to occipital hypoperfusion, preserved metabolism of the posterior
cingulate gyri (PCG) relative to the precunei is known as the cingulate island sign (CIS) in …

[HTML][HTML] FDG PET metabolic signatures distinguishing prodromal DLB and prodromal AD

K Kantarci, BF Boeve, SA Przybelski, TG Lesnick… - NeuroImage: Clinical, 2021 - Elsevier
Abstract Background and Purpose Patients with dementia with Lewy bodies (DLB) are
characterized by hypometabolism in the parieto–occipital cortex and the cingulate island …

[HTML][HTML] Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: associations with clinical severity, glucose metabolism and tau PET

Z Nedelska, ML Senjem, SA Przybelski, TG Lesnick… - NeuroImage: Clinical, 2018 - Elsevier
Visually preserved metabolism in posterior cingulate cortex relative to hypometabolism in
precuneus and cuneus, the cingulate island sign, is a feature of dementia with Lewy bodies …

Differentiating mild cognitive impairment, Alzheimer's disease, and dementia with Lewy bodies using cingulate island sign on perfusion IMP-SPECT

H Kanetaka, S Shimizu, Y Inagawa, D Hirose… - Frontiers in …, 2020 - frontiersin.org
The cingulate island sign (CIS) on fludeoxyglucose (FDG)-positron emission tomography
(PET) is a supporting biomarker of dementia with Lewy bodies (DLB). Its diagnostic accuracy …