Optimization and validation of direct gas chromatography-mass spectrometry method for simultaneous quantification of ten short-chain fatty acids in rat feces

JH Zhu, Q Mao, SY Wang, H Liu, SS Zhou… - … of Chromatography A, 2022 - Elsevier
Short-chain fatty acids (SCFAs) play key roles in maintaining health and treating disease.
Quantification of important fecal SCFAs is necessary to facilitate the clarification of their …

Rapid and accurate simultaneous determination of seven short-chain fatty acids in feces by gas chromatography–mass spectrometry (GC-MS): application in type 2 …

H Wang, Y Liu, J Shao, Y Luo, W Cai, L Chen - Analytical Letters, 2020 - Taylor & Francis
Short-chain fatty acids (SCFAs) are carboxylic acids that contain fewer than six carbons and
are the metabolites of the intestinal flora. SCFAs participate in almost all circulatory system …

Simultaneous quantification of eleven short-chain fatty acids by derivatization and solid phase microextraction-gas chromatography tandem mass spectrometry

Z Fu, Q Jia, H Zhang, L Kang, X Sun, M Zhang… - … of Chromatography A, 2022 - Elsevier
As metabolites of the gut microbiome, short-chain fatty acids (SCFAs) played an important
role in the diagnosis of the metabolic diseases. Because of the high polarity, high volatility …

[HTML][HTML] Analytical factors for eight short-chain fatty acid analyses in mouse feces through headspace solid-phase microextraction–triple quadrupole gas …

S Kang, J Yun, HY Park, JE Lee - Analytical and Bioanalytical Chemistry, 2023 - Springer
This study developed a method for quantifying eight short-chain fatty acids (SCFAs) in
mouse fecal samples using solid-phase microextraction (SPME) coupled with triple …

An in situ extraction and derivatization method for rapid analysis of short-chain fatty acids in rat fecal samples by gas chromatography tandem mass spectrometry

NH Park, MS Kim, W Lee, ME Lee, J Hong - Analytical Methods, 2017 - pubs.rsc.org
Short-chain fatty acids (SCFAs) are major products of gut microbial fermentation and
changes in their levels in a biological system reflect the progress of various diseases …

Fast quantification of short‐chain fatty acids in rat plasma by gas chromatography

CY Wang, YW Chen, YL Tain, SKC Chang… - Journal of food …, 2020 - Wiley Online Library
Short‐chain fatty acids (SCFAs) are the main metabolites of the intestinal flora and play an
important role in the interaction between the intestinal flora and host metabolism. Therefore …

A rapid and convenient derivatization method for quantitation of short‐chain fatty acids in human feces by ultra‐performance liquid chromatography/tandem mass …

H Fu, Q Zhang, X Huang, Z Ma, X Zheng… - Rapid …, 2020 - Wiley Online Library
Rationale Short‐chain fatty acids (SCFAs) are associated with intestinal microbiota and
diseases in humans. SCFAs have a low response in mass spectrometry, and in order to …

An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography–tandem mass spectrometry

J Han, K Lin, C Sequeira, CH Borchers - Analytica chimica acta, 2015 - Elsevier
Short-chain fatty acids (SCFAs) are produced by anaerobic gut microbiota in the large
bowel. Qualitative and quantitative measurements of SCFAs in the intestinal tract and the …

Rapid detection of short-chain fatty acids in biological samples

C Zhang, L Fan, H Zhao - Chromatographia, 2020 - Springer
An increasing number of researchers are focusing on short-chain fatty acids (SCFAs), which
are closely related to various aspects of the human body. This study presented a …

Gas chromatography detection protocol of short-chain fatty acids in mice feces

C Zhang, A Liu, T Zhang, Y Li, H Zhao - Bio-protocol, 2020 - bio-protocol.org
Short-chain fatty acids (SCFAs), which are formed mainly by bacteria fermenting undigested
carbohydrates in the colon, they are based on the number of carbon atoms in the carbon …