Role of mitochondria in diabetic peripheral neuropathy: Influencing the NAD+-dependent SIRT1–PGC-1α–TFAM pathway
K Chandrasekaran, M Anjaneyulu, J Choi… - International review of …, 2019 - Elsevier
Survival of human peripheral nervous system neurons and associated distal axons is highly
dependent on energy. Diabetes invokes a maladaptation in glucose and lipid energy …
dependent on energy. Diabetes invokes a maladaptation in glucose and lipid energy …
Mitochondrial dysfunction in diabetic neuropathy: a series of unfortunate metabolic events
P Fernyhough - Current diabetes reports, 2015 - Springer
Diabetic neuropathy is a dying back neurodegenerative disease of the peripheral nervous
system where mitochondrial dysfunction has been implicated as an etiological factor …
system where mitochondrial dysfunction has been implicated as an etiological factor …
Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes
Diabetic neuropathy is a major complication of diabetes that results in the progressive
deterioration of the sensory nervous system. Mitochondrial dysfunction has been proposed …
deterioration of the sensory nervous system. Mitochondrial dysfunction has been proposed …
The role of aberrant mitochondrial bioenergetics in diabetic neuropathy
SKR Chowdhury, DR Smith, P Fernyhough - Neurobiology of Disease, 2013 - Elsevier
Diabetic neuropathy is a neurological complication of diabetes that causes significant
morbidity and, because of the obesity-driven rise in incidence of type 2 diabetes, is …
morbidity and, because of the obesity-driven rise in incidence of type 2 diabetes, is …
Mitochondrial stress and the pathogenesis of diabetic neuropathy
P Fernyhough, SK Roy Chowdhury… - Expert review of …, 2010 - Taylor & Francis
Diabetic neuropathy is a major complication of diabetes that affects the sensory and
autonomic nervous systems and leads to significant morbidity and impact on the quality of …
autonomic nervous systems and leads to significant morbidity and impact on the quality of …
Mechanism of mitochondrial dysfunction in diabetic sensory neuropathy
P Fernyhough, TJ Huang… - Journal of the Peripheral …, 2003 - Wiley Online Library
Symmetrical sensory polyneuropathy, the most common form of diabetic neuropathy in
humans, is associated with a spectrum of structural changes in peripheral nerve that …
humans, is associated with a spectrum of structural changes in peripheral nerve that …
Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral …
Mitochondrial dysfunction occurs in sensory neurons and may contribute to distal
axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate …
axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate …
Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy
GM Leinninger, JL Edwards, MJ Lipshaw… - Nature Clinical Practice …, 2006 - nature.com
Diabetic neuropathy (DN) is the most common complication of diabetes mellitus, and it
imposes a considerable burden on a patient's quality of life and the health-care system …
imposes a considerable burden on a patient's quality of life and the health-care system …
Disorders of mitochondrial dynamics in peripheral neuropathy: clues from hereditary neuropathy and diabetes
AE Rumora, MG Savelieff, SA Sakowski… - International Review of …, 2019 - Elsevier
Peripheral neuropathy is a common and debilitating complication of diabetes and
prediabetes. Recent clinical studies have identified an association between the …
prediabetes. Recent clinical studies have identified an association between the …
Mitochondrial transcription factor A regulation of mitochondrial degeneration in experimental diabetic neuropathy
K Chandrasekaran, M Anjaneyulu… - American journal …, 2015 - journals.physiology.org
Oxidative stress-induced mitochondrial dysfunction and mitochondrial DNA (mtDNA)
damage in peripheral neurons is considered to be important in the development of diabetic …
damage in peripheral neurons is considered to be important in the development of diabetic …