The association between analgesic drug use in pregnancy and neurodevelopmental disorders: protocol for an umbrella review

J Kwok, HA Hall, AL Murray, B Auyeung - Systematic Reviews, 2020 - Springer
Background Maternal prenatal health has been shown to be an important influence on
children's developmental outcomes, which has led to an increased emphasis on providing …

[HTML][HTML] Analgesic drug use in pregnancy and neurodevelopment outcomes: an umbrella review

J Kwok, E Luedecke, HA Hall, AL Murray… - … & Biobehavioral Reviews, 2022 - Elsevier
Emerging evidence from reviews suggests that analgesic drug exposure during pregnancy
may contribute to child neurodevelopment outcomes. A comprehensive overview of existing …

Use and validity of child neurodevelopment outcome measures in studies on prenatal exposure to psychotropic and analgesic medications–A systematic review

S Hjorth, R Bromley, E Ystrom, A Lupattelli, O Spigset… - PLoS …, 2019 - journals.plos.org
In recent years there has been increased attention to child neurodevelopment in studies on
medication safety in pregnancy. Neurodevelopment is a multifactorial outcome that can be …

Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid‐childhood executive function and behaviour

SL Rifas‐Shiman, A Cardenas… - Paediatric and …, 2020 - Wiley Online Library
Background Over‐the‐counter analgesics during pregnancy or infancy may be related to
neurobehavioural problems in children, but little is known about effects of different analgesic …

Association of maternal prenatal acetaminophen use with the risk of attention deficit/hyperactivity disorder in offspring: A meta-analysis

X Gou, Y Wang, Y Tang, Y Qu, J Tang… - Australian & New …, 2019 - journals.sagepub.com
Background: Acetaminophen is a widely used medication for fever and pain management
during pregnancy. However, recent studies have found a possible connection between …

Prenatal paracetamol exposure and child neurodevelopment: A review

AZ Bauer, D Kriebel, MR Herbert, CG Bornehag… - Hormones and …, 2018 - Elsevier
Background The non-prescription medication paracetamol (acetaminophen, APAP) is
currently recommended as a safe pain and fever treatment during pregnancy. However …

Acetaminophen Use During Pregnancy and Children's Risk of Autism, ADHD, and Intellectual Disability

VH Ahlqvist, H Sjöqvist, C Dalman, H Karlsson… - Jama, 2024 - jamanetwork.com
Importance Several studies suggest that acetaminophen (paracetamol) use during
pregnancy may increase risk of neurodevelopmental disorders in children. If true, this would …

Prenatal exposure to non‐steroidal anti‐inflammatory drugs (NSAIDs) and neurodevelopmental outcomes in children

M Markovic, SA Swanson, BH Stricker… - … and drug safety, 2019 - Wiley Online Library
Purpose Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used during
pregnancy. Findings that prenatal NSAID exposure may affect offspring neurodevelopment …

In utero acetaminophen exposure and child neurodevelopmental outcomes: Systematic review and meta‐analysis

C Ricci, CM Albanese, LA Pablo, J Li… - Paediatric and …, 2023 - Wiley Online Library
Background Acetaminophen is a frequently used analgesic for pain and fever. There have
been reports of adverse neurodevelopmental outcomes associated with in utero …

Maternal use of antidepressant or anxiolytic medication during pregnancy and childhood neurodevelopmental outcomes: a systematic review

H El Marroun, T White, FC Verhulst… - European child & …, 2014 - Springer
Antidepressant and anxiolytic medications are widely prescribed and used by pregnant
women for acute and maintenance therapy. These drugs are able to pass the placental …