A defining feature of eukaryotic cells is the presence of a nuclear envelope separating
transcription and DNA replication in the nucleus from the site of protein synthesis in the …

Eukaryotic cells export several different classes of RNA molecule from the nucleus, where
they are transcribed, to the cytoplasm, where the majority participate in different aspects of …

One of the most profound differences between prokaryotes and eukaryotes is that only the
latter segregate RNA synthesis and protein synthesis into distinct cellular compartments, ie …

Nuclear mRNA export through the nuclear pore complex has been proposed to be a
unidirectional, signal-mediated and energy-dependent process. Evidence exists that this …

In eukaryotes, the separation of translation from transcription by the nuclear envelope
enables mRNA modifications such as capping, splicing, and polyadenylation. These …

The advent of the nucleus during the evolutionary development of the eukaryotic cell
necessitated the development of a transport system to convey messenger RNA (mRNA) from …

Cellular mRNAs are produced in the nucleus and must be exported to the cytoplasm to allow
for their translation into proteins. Recruitment of export factors to nascent mRNA starts …

The presence of the nuclear envelope necessitates the movement of proteins and RNAs
between the nucleus and the cytoplasm. Elaborate cellular machinery exists to promote the …

Eukaryotic gene expression is controlled by multiple mechanisms, and its regulation is
central for physiological responses to extracellular and intracellular signals. An essential …

Export of mRNA from the nucleus to the cytoplasm is a critical process for all eukaryotic gene
expression. As mRNA is synthesized, it is packaged with a myriad of RNA‐binding proteins …