Cryptococcus neoformans survives host temperature and regulates cell wall integrity via a
calcium-dependent phosphatase, calcineurin. However, downstream effectors of C …

The Ras1 signal transduction pathway controls the ability of the pathogenic fungus
Cryptococcus neoformans to grow at high temperatures and to mate. A second RAS gene …

The human pathogen Cryptococcus neoformans causes meningo-encephalitis. The
polysaccharide capsule is an important virulence factor for this yeast-like fungus. Previously …

The fungal pathogen Cryptococcus neoformans has three major virulence factors: growth at
37° C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al.(2008) employed …

Eukaryotic cells utilize complex signaling systems to detect their environments, responding
and adapting as new conditions arise during evolution. The basidiomycete fungus …

The polysaccharide capsule is one of the established virulence factors in Cryptococcus
neoformans that provides a barrier against the host-mediated immune response. Mutation of …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …

The human fungal pathogen Cryptococcus neoformans is able to rapidly and effectively
adapt to varying conditions, favoring its survival in the environment and in the infected host …

The fungal pathogen Cryptococcus neoformans survives phagocytosis by macrophages and
proliferates within, ultimately establishing latent infection as a facultative intracellular …

Cryptococcus neoformans is a basidiomycete yeast and opportunistic human pathogen of
increasing clinical importance due to the increasing population of immunocompromised …