Adaptation to host temperature is a prerequisite for any pathogen capable of causing deep
infection in humans. Our previous studies demonstrated that a Cryptococcus neoformans …

A pet cockatoo was the suspected source of Cryptococcus neoformans recovered from an
immunocompromised patient with cryptococcosis based on molecular analyses available in …

Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills almost
200,000 people worldwide each year. It is acquired when mammalian hosts inhale the …

Developmental processes are essential for the normal life cycles of many pathogenic fungi,
and they can facilitate survival in challenging environments, including the human host …

Cryptococcus neoformans capsule structure modifications after prolonged in vitro growth or
in vivo passaging have been reported previously. However, nothing is known about the …

Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …

Spores are essential particles for the survival of many organisms, both prokaryotic and
eukaryotic. Among the eukaryotes, fungi have developed spores with superior resistance …

Phenotypic switching has been described in serotype A and D strains of Cryptococcus
neoformans. It occurs in vivo during chronic infection and is associated with differential gene …

The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each
year. Survival of this basidiomycete at host CO 2 concentrations has only recently been …

Acidification of vesicular compartments plays an important role in a number of cellular
transport processes, including protein secretion, metal cofactor insertion, glycosylation and …